A case of primary malignant fibrous histiocytoma of the diaphragm

Jaejun Shim, Yongseon Cho, Hyun Sook Kim, Hye Sook Choi, Cheon Woong Choi, Jee Hong Yoo, Hong Mo Kang, Moon Ho Yang

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1 Citation (Scopus)


A malignant fibrous histiocytoma (MFH) is a major subset of soft tissue sarcomas, which occurs principally on the extremities or in the retroperitoneum, as well as on the head and neck of elderly patient. However, it is an extremely rare event when a MFH occurs primarily in the diaphragm of a young people. A 25-year-old woman visited our hospital complaining of right chest pain. The chest X-ray showed a diaphragmatic mass. An exploratory thoracotomic biopsy revealed a primary MFH of the diaphragm. The patient was treated with combined chemotherapy consisting of ifosfamide and doxorubicin. A partial response was seen after 6 cycles of chemotherapy. However, she died of brain metastasis 12 months after the diagnosis.

Original languageEnglish
Pages (from-to)645-650
Number of pages6
JournalTuberculosis and Respiratory Diseases
Issue number6
Publication statusPublished - 1 Jun 2003


  • Diaphragm
  • Fibrous Histiocytoma


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