A new cyclic tetrapeptide from the jellyfish-derived fungus Phoma sp.

Eun La Kim; Jian Lin Li; Bin Xiao; Jongki Hong; Eun Sook Yoo; Won Duk Yoon; Jee H. Jung

doi:10.1248/cpb.c12-00335

A new cyclic tetrapeptide from the jellyfish-derived fungus Phoma sp.

Eun La Kim, Jian Lin Li, Bin Xiao, Jongki Hong, Eun Sook Yoo, Won Duk Yoon, Jee H. Jung

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A new cyclic tetrapeptide (1), along with known congeners (2, 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai . The absolute configuration of 1 was determined using the modified Mosher's method and Marfey's method. Compound 1 displayed a weak suppressive effect on the production of nitric oxide (NO) in murine macrophage cells (RAW264.7) without notable cytotoxicity.

Original language	English
Pages (from-to)	1590-1593
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	60
Issue number	12
DOIs	https://doi.org/10.1248/cpb.c12-00335
Publication status	Published - 2012

Keywords

Cyclic tetrapeptide
Jellyfish-derived fungus
Nemopilema nomurai
Nitric oxide
Phoma sp.
Tentoxin

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10.1248/cpb.c12-00335

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abstract = "A new cyclic tetrapeptide (1), along with known congeners (2, 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai . The absolute configuration of 1 was determined using the modified Mosher's method and Marfey's method. Compound 1 displayed a weak suppressive effect on the production of nitric oxide (NO) in murine macrophage cells (RAW264.7) without notable cytotoxicity.",

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AU - Hong, Jongki

AU - Yoo, Eun Sook

AU - Yoon, Won Duk

AU - Jung, Jee H.

PY - 2012

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KW - Jellyfish-derived fungus

KW - Nemopilema nomurai

KW - Nitric oxide

KW - Phoma sp.

KW - Tentoxin

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A new cyclic tetrapeptide from the jellyfish-derived fungus Phoma sp.

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Keywords

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