TY - JOUR
T1 - A practical approach towards causality mining in clinical text using active transfer learning
AU - Hussain, Musarrat
AU - Satti, Fahad Ahmed
AU - Hussain, Jamil
AU - Ali, Taqdir
AU - Ali, Syed Imran
AU - Bilal, Hafiz Syed Muhammad
AU - Park, Gwang Hoon
AU - Lee, Sungyoung
AU - Chung, Tae Choong
N1 - Funding Information:
This research was supported by the MSIT (Ministry of Science and ICT), Korea, under the ITRC(Information Technology Research Center) support program (IITP-2017-0-01629) supervised by the IITP (Institute for Information & communications Technology Promotion), by the Korea government MSIT (Ministry of Science and ICT) grant (No. 2017-0-00655), by the MSIT Korea, under the Grant Information Technology Research Center support program (IITP-2020-0-01489), (IITP-2021-0-00979) supervised by the IITP (Institute for Information & communications Technology Planning & Evaluation) and NRF2019R1A2C2090504.
Publisher Copyright:
© 2021
PY - 2021/11
Y1 - 2021/11
N2 - Objective: Causality mining is an active research area, which requires the application of state-of-the-art natural language processing techniques. In the healthcare domain, medical experts create clinical text to overcome the limitation of well-defined and schema driven information systems. The objective of this research work is to create a framework, which can convert clinical text into causal knowledge. Methods: A practical approach based on term expansion, phrase generation, BERT based phrase embedding and semantic matching, semantic enrichment, expert verification, and model evolution has been used to construct a comprehensive causality mining framework. This active transfer learning based framework along with its supplementary services, is able to extract and enrich, causal relationships and their corresponding entities from clinical text. Results: The multi-model transfer learning technique when applied over multiple iterations, gains substantial performance improvements. We also present a comparative analysis of the presented techniques with their common alternatives, which demonstrate the correctness of our approach and its ability to capture most causal relationships. Conclusion: The presented framework has provided cutting-edge results in the healthcare domain. However, the framework can be tweaked to provide causality detection in other domains, as well. Significance: The presented framework is generic enough to be utilized in any domain, healthcare services can gain massive benefits due to the voluminous and various nature of its data. This causal knowledge extraction framework can be used to summarize clinical text, create personas, discover medical knowledge, and provide evidence to clinical decision making.
AB - Objective: Causality mining is an active research area, which requires the application of state-of-the-art natural language processing techniques. In the healthcare domain, medical experts create clinical text to overcome the limitation of well-defined and schema driven information systems. The objective of this research work is to create a framework, which can convert clinical text into causal knowledge. Methods: A practical approach based on term expansion, phrase generation, BERT based phrase embedding and semantic matching, semantic enrichment, expert verification, and model evolution has been used to construct a comprehensive causality mining framework. This active transfer learning based framework along with its supplementary services, is able to extract and enrich, causal relationships and their corresponding entities from clinical text. Results: The multi-model transfer learning technique when applied over multiple iterations, gains substantial performance improvements. We also present a comparative analysis of the presented techniques with their common alternatives, which demonstrate the correctness of our approach and its ability to capture most causal relationships. Conclusion: The presented framework has provided cutting-edge results in the healthcare domain. However, the framework can be tweaked to provide causality detection in other domains, as well. Significance: The presented framework is generic enough to be utilized in any domain, healthcare services can gain massive benefits due to the voluminous and various nature of its data. This causal knowledge extraction framework can be used to summarize clinical text, create personas, discover medical knowledge, and provide evidence to clinical decision making.
KW - Active transfer learning
KW - Causality mining
KW - Clinical text mining
KW - Machine learning
UR - http://www.scopus.com/inward/record.url?scp=85116896673&partnerID=8YFLogxK
U2 - 10.1016/j.jbi.2021.103932
DO - 10.1016/j.jbi.2021.103932
M3 - Article
C2 - 34628064
AN - SCOPUS:85116896673
VL - 123
JO - Journal of Biomedical Informatics
JF - Journal of Biomedical Informatics
SN - 1532-0464
M1 - 103932
ER -