Abstract
Breast cancer (BC) is one of the most common malignant cancers among women and the second leading cause of cancer-related deaths. Conventional treatments for BC are effective; however, they have several drawbacks, such as poor bioavailability and substantial side effects. On the other hand, using drug delivery systems (DDSs) have numerous benefits, such as suitable cancer targeting, reduced side effects, and controlled drug release. In recent years, DDSs have become a hotspot for the delivery of anti-BC drugs. The purpose of this review is to explore the progress of recent research on anti-BC drugs and the applications of polymer nanocomposites (PNCs) as DDSs for the treatment of BC. Moreover, this review summarizes important advances in the synthesis, preparation, and application of PNCs, using various nanomaterials and polymers, as nanocarriers for the treatment of BC. The challenges and opportunities associated with future clinical applications of PNCs in the treatment of BC are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 490-527 |
| Number of pages | 38 |
| Journal | Polymer Reviews |
| Volume | 64 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2024 |
Bibliographical note
Publisher Copyright:© 2023 Taylor & Francis Group, LLC.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy
Keywords
- Polymer nanocomposite
- breast cancer
- controlled release
- drug carriers
- drug delivery systems
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