Acetylcholinesterase-responsive fluorescent probe: Recent advances from development to applications

Jong Min An; Kyung Oh Jung; Myung Sook Oh; Dokyoung Kim

doi:10.1016/j.dyepig.2023.111267

Acetylcholinesterase-responsive fluorescent probe: Recent advances from development to applications

Jong Min An, Kyung Oh Jung, Myung Sook Oh, Dokyoung Kim

Research output: Contribution to journal › Review article › peer-review

13 Citations (Scopus)

Abstract

The correlation between diseases and acetylcholinesterase (AChE) has been highlighted in the medical field. In this regard, the AChE-responsive fluorescent probes can enhance the prevention of unexpected human diseases. Herein, we discuss the recent advances in AChE-responsive fluorescent probes capable of detecting the AChE expression and monitoring the AChE activity in real time. The fluorescent probes for AChE can be categorized into three parts based on the AChE sensing rationale. Photophysical properties of the AChE-responsive fluorescent probes and representative examples of the proof-of-concept AChE-related visualization studies are also summarized. We hope that this review will inspire the development of AChE-responsive fluorescent probes and contribute to improving overall health conditions worldwide.

Original language	English
Article number	111267
Journal	Dyes and Pigments
Volume	215
DOIs	https://doi.org/10.1016/j.dyepig.2023.111267
Publication status	Published - Jul 2023

Bibliographical note

Publisher Copyright:
© 2023

Keywords

Acetylcholinesterase
Enzymatic reaction
Fluorescence imaging
Fluorescent probe

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.dyepig.2023.111267

Cite this

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title = "Acetylcholinesterase-responsive fluorescent probe: Recent advances from development to applications",

abstract = "The correlation between diseases and acetylcholinesterase (AChE) has been highlighted in the medical field. In this regard, the AChE-responsive fluorescent probes can enhance the prevention of unexpected human diseases. Herein, we discuss the recent advances in AChE-responsive fluorescent probes capable of detecting the AChE expression and monitoring the AChE activity in real time. The fluorescent probes for AChE can be categorized into three parts based on the AChE sensing rationale. Photophysical properties of the AChE-responsive fluorescent probes and representative examples of the proof-of-concept AChE-related visualization studies are also summarized. We hope that this review will inspire the development of AChE-responsive fluorescent probes and contribute to improving overall health conditions worldwide.",

keywords = "Acetylcholinesterase, Enzymatic reaction, Fluorescence imaging, Fluorescent probe",

author = "An, {Jong Min} and Jung, {Kyung Oh} and Oh, {Myung Sook} and Dokyoung Kim",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

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doi = "10.1016/j.dyepig.2023.111267",

language = "English",

volume = "215",

journal = "Dyes and Pigments",

issn = "0143-7208",

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TY - JOUR

T1 - Acetylcholinesterase-responsive fluorescent probe

T2 - Recent advances from development to applications

AU - An, Jong Min

AU - Jung, Kyung Oh

AU - Oh, Myung Sook

AU - Kim, Dokyoung

PY - 2023/7

Y1 - 2023/7

N2 - The correlation between diseases and acetylcholinesterase (AChE) has been highlighted in the medical field. In this regard, the AChE-responsive fluorescent probes can enhance the prevention of unexpected human diseases. Herein, we discuss the recent advances in AChE-responsive fluorescent probes capable of detecting the AChE expression and monitoring the AChE activity in real time. The fluorescent probes for AChE can be categorized into three parts based on the AChE sensing rationale. Photophysical properties of the AChE-responsive fluorescent probes and representative examples of the proof-of-concept AChE-related visualization studies are also summarized. We hope that this review will inspire the development of AChE-responsive fluorescent probes and contribute to improving overall health conditions worldwide.

AB - The correlation between diseases and acetylcholinesterase (AChE) has been highlighted in the medical field. In this regard, the AChE-responsive fluorescent probes can enhance the prevention of unexpected human diseases. Herein, we discuss the recent advances in AChE-responsive fluorescent probes capable of detecting the AChE expression and monitoring the AChE activity in real time. The fluorescent probes for AChE can be categorized into three parts based on the AChE sensing rationale. Photophysical properties of the AChE-responsive fluorescent probes and representative examples of the proof-of-concept AChE-related visualization studies are also summarized. We hope that this review will inspire the development of AChE-responsive fluorescent probes and contribute to improving overall health conditions worldwide.

KW - Acetylcholinesterase

KW - Enzymatic reaction

KW - Fluorescence imaging

KW - Fluorescent probe

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U2 - 10.1016/j.dyepig.2023.111267

DO - 10.1016/j.dyepig.2023.111267

M3 - Review article

AN - SCOPUS:85150868370

SN - 0143-7208

VL - 215

JO - Dyes and Pigments

JF - Dyes and Pigments

M1 - 111267

ER -

Acetylcholinesterase-responsive fluorescent probe: Recent advances from development to applications

Abstract

Bibliographical note

Keywords

UN SDGs

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Findings from Kyung Hee University Yields New Data on Dye and Pigment Research (Acetylcholinesterase-responsive Fluorescent Probe: Recent Advances From Development To Applications)

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Acetylcholinesterase-responsive fluorescent probe: Recent advances from development to applications

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

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Findings from Kyung Hee University Yields New Data on Dye and Pigment Research (Acetylcholinesterase-responsive Fluorescent Probe: Recent Advances From Development To Applications)

Cite this