Abstract
The discovery of adult neurogenesis was a turning point in the field of neuroscience. Adult neurogenesis offers an enormous possibility to open a new therapeutic paradigm of neurodegenerative diseases and stroke. Recently, several studies suggested that acupuncture may enhance adult neurogenesis. Acupuncture has long been an important treatment for brain diseases in the East Asia. The scientific mechanisms of acupuncture treatment for the diseases, such as Alzheimer's disease, Parkinson's disease, and stroke, have not been clarified yet; however, the neurogenic effect of acupuncture can be a possible reason. Here, we have reviewed the studies on the effect of stimulation at various acupoints for neurogenesis, such as ST36 and GV20. The suggested mechanisms are also discussed including upregulation of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, basic fibroblast growth factor and neuropeptide Y, and activation of the function of primo vascular system.
| Original language | English |
|---|---|
| Title of host publication | International Review of Neurobiology |
| Publisher | Academic Press Inc. |
| Pages | 67-90 |
| Number of pages | 24 |
| DOIs | |
| Publication status | Published - 2013 |
Publication series
| Name | International Review of Neurobiology |
|---|---|
| Volume | 111 |
| ISSN (Print) | 0074-7742 |
Bibliographical note
Funding Information:This work was supported by the project of National Junior Research Fellowship, which National Research Foundation of Korea conducts from 2012.
Keywords
- Acupuncture
- Adult neurogenesis
- Alzheimer's disease
- Parkinson's disease
- Stroke