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Adalimumab treatment may replace or enhance the activity of steroids in steroid-refractory tuberculous meningitis

  • Ho Su Lee
  • , Yumi Lee
  • , Sang Oh Lee
  • , Sang Ho Choi
  • , Yang Soo Kim
  • , Jun Hee Woo
  • , Sung Han Kim

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

We describe a paradoxical response involving the central nervous system in a patient with steroid-refractory tuberculousmeningitis that was unresponsive to systemic corticosteroids but was improved with adalimumab. The immunomodulatory effect oftumor necrosis factor inhibitors may have a role in replacing or enhancing the activity of steroids in the management ofsteroid-refractory tuberculous meningitis.

Original languageEnglish
Pages (from-to)555-557
Number of pages3
JournalJournal of Infection and Chemotherapy
Volume18
Issue number4
DOIs
Publication statusPublished - Aug 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Adalimumab
  • Paradoxical reaction
  • Steroid-refractory
  • Tuberculosis
  • Tumor necrosis factor inhibitor

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