Anaerobic membrane bioreactor performance with varying feed concentrations of ciprofloxacin

Thi Mai Do, Donggeon Choi, Seungdae Oh, David C. Stuckey

Research output: Contribution to journalArticlepeer-review


The anaerobic membrane bioreactor (AnMBR) has considerable potential for treating wastewater, although there is very little data on the effect of antibiotics on AnMBR performance. This study examined the effect of Ciprofloxacin (CIP) - an antibiotic that can occur at high concentrations, and has a substantial impact on ecosystems, on AnMBR performance. The long-term (44 days) presence of 0.5 mg/L CIP in the feed did not have a strong effect on COD removal, volatile fatty acid (VFA) accumulation, or methane yield, but did affect the pH, soluble microbial products (SMPs) and suspended solids. However, at 4.7 mg/L CIP, a significant effect on all the parameters tested was seen. 16S rRNA gene-based community analysis demonstrated that CIP changed the phylogenetic structure and altered the species richness and diversity. The relative abundance of various genera was also changed, and this explained much of the change in AnMBR behavior.

Original languageEnglish
Article number150108
JournalScience of the Total Environment
Publication statusPublished - 10 Jan 2022


  • 16S rRNA gene-based community analysis
  • Anaerobic membrane bioreactor (AnMBR)
  • Ciprofloxacin (CIP)
  • Performance


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