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Analogs of glutamic acid: Synthesis and biological evaluation

  • George A. Kraus
  • , Hakwon Kim
  • , P. J. Thomas
  • , D. E. David
  • , M. Metzler

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

The reaction of bromodiester 6 with base in liquid ammonia affords good yields of aminocyclopropane diesters 8 and 9. The corresponding diacids were not inhibitors of AAT.

Original languageEnglish
Pages (from-to)2667-2673
Number of pages7
JournalSynthetic Communications
Volume20
Issue number17
DOIs
Publication statusPublished - 1990

Bibliographical note

Funding Information:
Council for partial support of this research. DM also thanks the

Funding Information:
National Institutes of Health (grant number 01549) for partial

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