Abstract
The trabecular bone score (TBS) was introduced as an indirect index of trabecular microarchitecture, complementary to bone mineral density (BMD), and is derived using the same dual energy X-ray absorptiometry images. Recently, it has been approved for clinical use in Korea. Therefore, we conducted a comprehensive review to optimize the use of TBS in clinical practice. The TBS is an independent predictor of osteoporotic fractures in postmenopausal women and men aged >50 years. The TBS is potentially useful in monitoring the skeletal effects of anabolic agents but not of antiresorptive agents. In postmenopausal women with type 2 diabetes mellitus, the TBS assesses osteoporotic fracture risk not captured by BMD. However, high body mass index and soft tissue thickness can cause underestimation of the TBS; however, this limitation has been improved in recent versions of the TBS software. However, a high precision error and low reproducibility limit the use of TBS. This review may provide information on the application of the TBS in clinical practice based on reliable evidence.
| Original language | English |
|---|---|
| Pages (from-to) | 101-113 |
| Number of pages | 13 |
| Journal | Journal of Bone Metabolism |
| Volume | 28 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - May 2021 |
Bibliographical note
Publisher Copyright:Copyright © 2021 The Korean Society for Bone and Mineral Research
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancellous bone
- Hip fractures
- Osteoporosis
- Osteoporotic fractures
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