Abstract
Asthma–chronic obstructive pulmonary disease (COPD) overlap (ACO) is a mixed phenotype of airway disease that is characterized by a fixed airway obstruction in patients exhibiting features of both asthma and COPD. Although international guidelines have suggested several definitions of ACO, the prevalence and phenotypes of ACO remain unclear. Furthermore, patients with ACO often experience more frequent exacerbations, hospitalizations, and increased healthcare resource use than those with only asthma or COPD.1 It is still ambiguous to determine the definition and the management of ACO because it is not easy to manage patients of ACO such as "eosinophilic COPD" or "smoking asthma" and show refractoriness to current treatments.
| Original language | English |
|---|---|
| Article number | e247 |
| Journal | Journal of Korean Medical Science |
| Volume | 37 |
| Issue number | 30 |
| DOIs | |
| Publication status | Published - 2022 |
Bibliographical note
Publisher Copyright:© 2022. The Korean Academy of Medical Sciences. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.