Chronic myelogenous leukemia showing biphenotypic blast crisis followed by lineage switch to B lymphoblastic leukemia

Seung Hwan Oh; Tae Sung Park; Hye Ran Kim; Ja Young Lee; Jae Hyun Kim; Jeong Hwan Shin; Jeong Nyeo Lee

doi:10.1016/j.leukres.2009.04.026

Chronic myelogenous leukemia showing biphenotypic blast crisis followed by lineage switch to B lymphoblastic leukemia

Seung Hwan Oh, Tae Sung Park, Hye Ran Kim, Ja Young Lee, Jae Hyun Kim, Jeong Hwan Shin, Jeong Nyeo Lee

Research output: Contribution to journal › Letter › peer-review

12 Citations (Scopus)

Abstract

Lineage switch is a very rare event in blastic crisis of chronic myelogenous leukemia (CML-BC). To our knowledge, only three cases of lineage switch between lymphoid and myeloid/myelomonocytic lineages have been reported in the literature. Here, we report a novel case of imatinib-resistant CML-BC, in which the blast lineage switched from biphenotypic to B-lymphoid.

Original language	English
Pages (from-to)	e195-e198
Journal	Leukemia Research
Volume	33
Issue number	11
DOIs	https://doi.org/10.1016/j.leukres.2009.04.026
Publication status	Published - Nov 2009

Keywords

B lymphoblastic leukemia
Biphenotypic blast crisis
Chronic myelogenous leukemia
Lineage switch

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.leukres.2009.04.026

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@article{37acc2549e6149f58b619c323fd4e196,

title = "Chronic myelogenous leukemia showing biphenotypic blast crisis followed by lineage switch to B lymphoblastic leukemia",

abstract = "Lineage switch is a very rare event in blastic crisis of chronic myelogenous leukemia (CML-BC). To our knowledge, only three cases of lineage switch between lymphoid and myeloid/myelomonocytic lineages have been reported in the literature. Here, we report a novel case of imatinib-resistant CML-BC, in which the blast lineage switched from biphenotypic to B-lymphoid.",

keywords = "B lymphoblastic leukemia, Biphenotypic blast crisis, Chronic myelogenous leukemia, Lineage switch",

author = "Oh, {Seung Hwan} and Park, {Tae Sung} and Kim, {Hye Ran} and Lee, {Ja Young} and Kim, {Jae Hyun} and Shin, {Jeong Hwan} and Lee, {Jeong Nyeo}",

year = "2009",

month = nov,

doi = "10.1016/j.leukres.2009.04.026",

language = "English",

volume = "33",

pages = "e195--e198",

journal = "Leukemia Research",

issn = "0145-2126",

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TY - JOUR

T1 - Chronic myelogenous leukemia showing biphenotypic blast crisis followed by lineage switch to B lymphoblastic leukemia

AU - Oh, Seung Hwan

AU - Park, Tae Sung

AU - Kim, Hye Ran

AU - Lee, Ja Young

AU - Kim, Jae Hyun

AU - Shin, Jeong Hwan

AU - Lee, Jeong Nyeo

PY - 2009/11

Y1 - 2009/11

N2 - Lineage switch is a very rare event in blastic crisis of chronic myelogenous leukemia (CML-BC). To our knowledge, only three cases of lineage switch between lymphoid and myeloid/myelomonocytic lineages have been reported in the literature. Here, we report a novel case of imatinib-resistant CML-BC, in which the blast lineage switched from biphenotypic to B-lymphoid.

AB - Lineage switch is a very rare event in blastic crisis of chronic myelogenous leukemia (CML-BC). To our knowledge, only three cases of lineage switch between lymphoid and myeloid/myelomonocytic lineages have been reported in the literature. Here, we report a novel case of imatinib-resistant CML-BC, in which the blast lineage switched from biphenotypic to B-lymphoid.

KW - B lymphoblastic leukemia

KW - Biphenotypic blast crisis

KW - Chronic myelogenous leukemia

KW - Lineage switch

UR - http://www.scopus.com/inward/record.url?scp=68649098954&partnerID=8YFLogxK

U2 - 10.1016/j.leukres.2009.04.026

DO - 10.1016/j.leukres.2009.04.026

M3 - Letter

C2 - 19446879

AN - SCOPUS:68649098954

SN - 0145-2126

VL - 33

SP - e195-e198

JO - Leukemia Research

JF - Leukemia Research

IS - 11

ER -

Chronic myelogenous leukemia showing biphenotypic blast crisis followed by lineage switch to B lymphoblastic leukemia

Abstract

Keywords

UN SDGs

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