Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation

Hanna Lee; Jinho Choi; Amar Prasad Gupta; Jaeik Jung; Jaekyu Jang; Kyung Sik Yoon; Jehwang Ryu

doi:10.1117/12.2655840

Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation

Hanna Lee, Jinho Choi, Amar Prasad Gupta, Jaeik Jung, Jaekyu Jang, Kyung Sik Yoon, Jehwang Ryu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

We designed and developed a carbon nanotube (CNT)-based reflective digital cell irradiation system capable of irradiating cells. The chemical and physical properties of the CNT synthesized directly on the patterned substrate were confirmed, and the field emission characteristics with a maximum anode current of 10 mA were evaluated through the I-V curve. Also, electrostatic simulation was conducted to confirm the electric field distribution and the electron beam trajectory. According to the duty (27.3 mGy at anode on time 10 sec, duty 50 %), the anode voltage (25.2 mGy at anode on time 10 sec, duty 50 %, anode voltage 40 kV) and the distance between the window and the cell stage (anode on time 10 sec, duty 50%, anode voltage 40 kV, 19.4 mGy), the function of the system was verified by obtaining the dose emitted from the system. This study confirmed that it is suitable as the cell irradiation system for studying the radiobiological effects of low-dose radiation-irradiated cells.

Original language	English
Title of host publication	Medical Imaging 2023
Subtitle of host publication	Physics of Medical Imaging
Editors	Lifeng Yu, Rebecca Fahrig, John M. Sabol
Publisher	SPIE
ISBN (Electronic)	9781510660311
DOIs	https://doi.org/10.1117/12.2655840
Publication status	Published - 2023
Event	Medical Imaging 2023: Physics of Medical Imaging - San Diego, United States Duration: 19 Feb 2023 → 23 Feb 2023

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	12463
ISSN (Print)	1605-7422

Conference

Conference	Medical Imaging 2023: Physics of Medical Imaging
Country/Territory	United States
City	San Diego
Period	19/02/23 → 23/02/23

Bibliographical note

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

Keywords

CNT
Carbon Nanotube
Cell irradiation
Low-dose radiation
Point emitter

Access to Document

10.1117/12.2655840

Cite this

Lee, H., Choi, J., Gupta, A. P., Jung, J., Jang, J., Yoon, K. S., & Ryu, J. (2023). Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation. In L. Yu, R. Fahrig, & J. M. Sabol (Eds.), Medical Imaging 2023: Physics of Medical Imaging Article 124634M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12463). SPIE. https://doi.org/10.1117/12.2655840

Lee, Hanna ; Choi, Jinho ; Gupta, Amar Prasad et al. / Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation. Medical Imaging 2023: Physics of Medical Imaging. editor / Lifeng Yu ; Rebecca Fahrig ; John M. Sabol. SPIE, 2023. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

@inproceedings{146eaa9593a8498391ec3301bb8e039b,

title = "Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation",

abstract = "We designed and developed a carbon nanotube (CNT)-based reflective digital cell irradiation system capable of irradiating cells. The chemical and physical properties of the CNT synthesized directly on the patterned substrate were confirmed, and the field emission characteristics with a maximum anode current of 10 mA were evaluated through the I-V curve. Also, electrostatic simulation was conducted to confirm the electric field distribution and the electron beam trajectory. According to the duty (27.3 mGy at anode on time 10 sec, duty 50 %), the anode voltage (25.2 mGy at anode on time 10 sec, duty 50 %, anode voltage 40 kV) and the distance between the window and the cell stage (anode on time 10 sec, duty 50%, anode voltage 40 kV, 19.4 mGy), the function of the system was verified by obtaining the dose emitted from the system. This study confirmed that it is suitable as the cell irradiation system for studying the radiobiological effects of low-dose radiation-irradiated cells.",

keywords = "CNT, Carbon Nanotube, Cell irradiation, Low-dose radiation, Point emitter",

author = "Hanna Lee and Jinho Choi and Gupta, {Amar Prasad} and Jaeik Jung and Jaekyu Jang and Yoon, {Kyung Sik} and Jehwang Ryu",

note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Medical Imaging 2023: Physics of Medical Imaging ; Conference date: 19-02-2023 Through 23-02-2023",

year = "2023",

doi = "10.1117/12.2655840",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Lifeng Yu and Rebecca Fahrig and Sabol, {John M.}",

booktitle = "Medical Imaging 2023",

address = "United States",

}

Lee, H, Choi, J, Gupta, AP, Jung, J, Jang, J, Yoon, KS & Ryu, J 2023, Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation. in L Yu, R Fahrig & JM Sabol (eds), Medical Imaging 2023: Physics of Medical Imaging., 124634M, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 12463, SPIE, Medical Imaging 2023: Physics of Medical Imaging, San Diego, United States, 19/02/23. https://doi.org/10.1117/12.2655840

Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation. / Lee, Hanna; Choi, Jinho; Gupta, Amar Prasad et al.
Medical Imaging 2023: Physics of Medical Imaging. ed. / Lifeng Yu; Rebecca Fahrig; John M. Sabol. SPIE, 2023. 124634M (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12463).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation

AU - Lee, Hanna

AU - Choi, Jinho

AU - Gupta, Amar Prasad

AU - Jung, Jaeik

AU - Jang, Jaekyu

AU - Yoon, Kyung Sik

AU - Ryu, Jehwang

N1 - Publisher Copyright: © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

PY - 2023

Y1 - 2023

N2 - We designed and developed a carbon nanotube (CNT)-based reflective digital cell irradiation system capable of irradiating cells. The chemical and physical properties of the CNT synthesized directly on the patterned substrate were confirmed, and the field emission characteristics with a maximum anode current of 10 mA were evaluated through the I-V curve. Also, electrostatic simulation was conducted to confirm the electric field distribution and the electron beam trajectory. According to the duty (27.3 mGy at anode on time 10 sec, duty 50 %), the anode voltage (25.2 mGy at anode on time 10 sec, duty 50 %, anode voltage 40 kV) and the distance between the window and the cell stage (anode on time 10 sec, duty 50%, anode voltage 40 kV, 19.4 mGy), the function of the system was verified by obtaining the dose emitted from the system. This study confirmed that it is suitable as the cell irradiation system for studying the radiobiological effects of low-dose radiation-irradiated cells.

AB - We designed and developed a carbon nanotube (CNT)-based reflective digital cell irradiation system capable of irradiating cells. The chemical and physical properties of the CNT synthesized directly on the patterned substrate were confirmed, and the field emission characteristics with a maximum anode current of 10 mA were evaluated through the I-V curve. Also, electrostatic simulation was conducted to confirm the electric field distribution and the electron beam trajectory. According to the duty (27.3 mGy at anode on time 10 sec, duty 50 %), the anode voltage (25.2 mGy at anode on time 10 sec, duty 50 %, anode voltage 40 kV) and the distance between the window and the cell stage (anode on time 10 sec, duty 50%, anode voltage 40 kV, 19.4 mGy), the function of the system was verified by obtaining the dose emitted from the system. This study confirmed that it is suitable as the cell irradiation system for studying the radiobiological effects of low-dose radiation-irradiated cells.

KW - CNT

KW - Carbon Nanotube

KW - Cell irradiation

KW - Low-dose radiation

KW - Point emitter

UR - http://www.scopus.com/inward/record.url?scp=85160717369&partnerID=8YFLogxK

U2 - 10.1117/12.2655840

DO - 10.1117/12.2655840

M3 - Conference contribution

AN - SCOPUS:85160717369

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Medical Imaging 2023

A2 - Yu, Lifeng

A2 - Fahrig, Rebecca

A2 - Sabol, John M.

PB - SPIE

T2 - Medical Imaging 2023: Physics of Medical Imaging

Y2 - 19 February 2023 through 23 February 2023

ER -

Lee H, Choi J, Gupta AP, Jung J, Jang J, Yoon KS et al. Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation. In Yu L, Fahrig R, Sabol JM, editors, Medical Imaging 2023: Physics of Medical Imaging. SPIE. 2023. 124634M. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2655840

Development of reflective type digital cell irradiation system based on carbon nanotube for biological research of low-dose radiation

Abstract

Publication series

Conference

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this