Diabetic nephropathy – A review of risk factors, progression, mechanism, and dietary management

Vijayakumar Natesan, Sung Jin Kim

Research output: Contribution to journalReview articlepeer-review

105 Citations (Scopus)

Abstract

Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM. Extensive work is being done to delineate the pathogenesis of DN and to extend possible remedies. This review is intended to understand the nature of DN risk factors, progression, effects of glycemic levels, and stages of DN. We also explored the novel diagnostic and therapeutic approaches for DN such as gene therapy and stem cell treatments.

Original languageEnglish
Pages (from-to)365-372
Number of pages8
JournalBiomolecules and Therapeutics
Volume29
Issue number4
DOIs
Publication statusPublished - 2021

Bibliographical note

Publisher Copyright:
© 2021 The Korean Society of Applied Pharmacology.

Keywords

  • Diabetic nephropathy
  • Hyperglycemia
  • Kidney disease
  • Novel drugs

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