Effect of far infrared drying on antioxidant property, anti-inflammatory activity, and inhibitory activity in A549 cells of Gamguk (Chrysanthemum indicum L.) flower

Won Woo Kim; Amal Kumar Ghimeray; Jin Cheng Wu; Seok Hyun Eom; Beom Goo Lee; Wie Soo Kang; Dong Ha Cho

doi:10.1007/s10068-012-0034-0

Effect of far infrared drying on antioxidant property, anti-inflammatory activity, and inhibitory activity in A549 cells of Gamguk (Chrysanthemum indicum L.) flower

Won Woo Kim, Amal Kumar Ghimeray, Jin Cheng Wu, Seok Hyun Eom, Beom Goo Lee, Wie Soo Kang, Dong Ha Cho

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264. 7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E₂ (PGE₂) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0. 05) higher in dose and time dependent manner.

Original language	English
Pages (from-to)	261-265
Number of pages	5
Journal	Food Science and Biotechnology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1007/s10068-012-0034-0
Publication status	Published - Feb 2012

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Copyright 2013 Elsevier B.V., All rights reserved.

Keywords

A549
anti-inflammatory
far infrared ray
gamguk (Chrysanthemum indicum L.)
polyphenol

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10068-012-0034-0

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title = "Effect of far infrared drying on antioxidant property, anti-inflammatory activity, and inhibitory activity in A549 cells of Gamguk (Chrysanthemum indicum L.) flower",

abstract = "This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264. 7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E2 (PGE2) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0. 05) higher in dose and time dependent manner.",

keywords = "A549, anti-inflammatory, far infrared ray, gamguk (Chrysanthemum indicum L.), polyphenol",

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AU - Kim, Won Woo

AU - Ghimeray, Amal Kumar

AU - Wu, Jin Cheng

AU - Eom, Seok Hyun

AU - Lee, Beom Goo

AU - Kang, Wie Soo

AU - Cho, Dong Ha

PY - 2012/2

Y1 - 2012/2

N2 - This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264. 7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E2 (PGE2) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0. 05) higher in dose and time dependent manner.

AB - This research demonstrated and compared the effects of shade and far infrared drying (FIRD) of gamguk (Chrysanthemum indicum L., CE) flowers extract on total phenolic (TP), total flavonoid (TF) content, anticancer and anti-inflammatory activities. The research data revealed that the TP and TF contents were highest in FIRD treated CE flower extracts. Similarly, the effect of CE on lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264. 7 cells showed in a dose dependent manner. Further, the CE inhibited the tumor necorsis factor (TNF)-α, cyclooxygenase (COX)-2 expression, and prostaglandis E2 (PGE2) production. The anticancer activity was monitored in A549 lung cancer cell, which showed that FIRD treated CE inhibited cell proliferation significantly (p<0. 05) higher in dose and time dependent manner.

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KW - anti-inflammatory

KW - far infrared ray

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Effect of far infrared drying on antioxidant property, anti-inflammatory activity, and inhibitory activity in A549 cells of Gamguk (Chrysanthemum indicum L.) flower

Abstract

Bibliographical note

Keywords

UN SDGs

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