Effects of sodium tripolyphosphate on oral commensal and pathogenic bacteria

Ji Hoi Moon, Mi Hee Noh, Eun Young Jang, Seok Bin Yang, Sang Wook Kang, Kyu Hwan Kwack, Jae In Ryu, Jin Yong Lee

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Polyphosphate (polyP) is a food additive with antimicrobial activity. Here we evaluated the effects of sodium tripolyphosphate (polyP3, Na5P3O10) on four major oral bacterial species, in both single- and mixed-culture. PolyP3 inhibited three opportunistic pathogenic species: Fusobacterium nucleatum, Prevotella intermedia, and Porphyromonas gingivalis. On the contrary, a commensal bacterium Streptococcus gordonii was relatively less susceptible to polyP3 than the pathogens. When all bacterial species were co-cultured, polyP3 (≥ 0.09%) significantly reduced their total growth and biofilm formation, among which the three pathogenic bacteria were selectively inhibited. Collectively, polyP3 may be an alternative antibacterial agent to control oral pathogenic bacteria.

Original languageEnglish
Pages (from-to)263-268
Number of pages6
JournalPolish Journal of Microbiology
Volume68
Issue number2
DOIs
Publication statusPublished - 2019

Bibliographical note

Publisher Copyright:
© 2019 Ji-Hoi Moon et al.

Keywords

  • Antibacterial
  • Commensal
  • Oral bacteria
  • Pathogenic
  • Polyphosphate

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