Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus

Jian Lin Li; Eun La Kim; Haibo Wang; Jongki Hong; Sook Shin; Chong Kyo Lee; Jee H. Jung

doi:10.1016/j.bmcl.2013.05.097

Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus

Jian Lin Li
, Eun La Kim
, Haibo Wang
, Jongki Hong
, Sook Shin
, Chong Kyo Lee
, Jee H. Jung

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Investigation of the secondary metabolites of the ascidian Herdmania momus led to the isolation and characterization of four new nucleoside derivatives (1-4). Structural studies showed that these derivatives represent a series of rare methylsulfinyladenosine derivatives of interconvertible transesterification isomers and/or sulfinyl epimers. The antiviral activities of these rare nucleosides were evaluated against a series of human pathogenic viruses.

Original language	English
Pages (from-to)	4701-4704
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	23
Issue number	16
DOIs	https://doi.org/10.1016/j.bmcl.2013.05.097
Publication status	Published - 15 Aug 2013

Bibliographical note

Funding Information:
This study was supported by the National Research Foundation of Korea (Grant No. 20090083538 ).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Keywords

Ascidian
Herdmania momus
Nucleoside derivatives
Sulfinyl epimers

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10.1016/j.bmcl.2013.05.097

Cite this

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title = "Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus",

abstract = "Investigation of the secondary metabolites of the ascidian Herdmania momus led to the isolation and characterization of four new nucleoside derivatives (1-4). Structural studies showed that these derivatives represent a series of rare methylsulfinyladenosine derivatives of interconvertible transesterification isomers and/or sulfinyl epimers. The antiviral activities of these rare nucleosides were evaluated against a series of human pathogenic viruses.",

keywords = "Ascidian, Herdmania momus, Nucleoside derivatives, Sulfinyl epimers",

author = "Li, \{Jian Lin\} and Kim, \{Eun La\} and Haibo Wang and Jongki Hong and Sook Shin and Lee, \{Chong Kyo\} and Jung, \{Jee H.\}",

note = "Funding Information: This study was supported by the National Research Foundation of Korea (Grant No. 20090083538 ). ",

year = "2013",

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day = "15",

doi = "10.1016/j.bmcl.2013.05.097",

language = "English",

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journal = "Bioorganic and Medicinal Chemistry Letters",

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T1 - Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus

AU - Li, Jian Lin

AU - Kim, Eun La

AU - Wang, Haibo

AU - Hong, Jongki

AU - Shin, Sook

AU - Lee, Chong Kyo

AU - Jung, Jee H.

N1 - Funding Information: This study was supported by the National Research Foundation of Korea (Grant No. 20090083538 ).

PY - 2013/8/15

Y1 - 2013/8/15

N2 - Investigation of the secondary metabolites of the ascidian Herdmania momus led to the isolation and characterization of four new nucleoside derivatives (1-4). Structural studies showed that these derivatives represent a series of rare methylsulfinyladenosine derivatives of interconvertible transesterification isomers and/or sulfinyl epimers. The antiviral activities of these rare nucleosides were evaluated against a series of human pathogenic viruses.

AB - Investigation of the secondary metabolites of the ascidian Herdmania momus led to the isolation and characterization of four new nucleoside derivatives (1-4). Structural studies showed that these derivatives represent a series of rare methylsulfinyladenosine derivatives of interconvertible transesterification isomers and/or sulfinyl epimers. The antiviral activities of these rare nucleosides were evaluated against a series of human pathogenic viruses.

KW - Ascidian

KW - Herdmania momus

KW - Nucleoside derivatives

KW - Sulfinyl epimers

UR - https://www.scopus.com/pages/publications/84880605660

U2 - 10.1016/j.bmcl.2013.05.097

DO - 10.1016/j.bmcl.2013.05.097

M3 - Article

C2 - 23810281

AN - SCOPUS:84880605660

SN - 0960-894X

VL - 23

SP - 4701

EP - 4704

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 16

ER -

Epimeric methylsulfinyladenosine derivatives from the marine ascidian Herdmania momus

Abstract

Bibliographical note

UN SDGs

Keywords

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