Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs

Chung Hyun Kim; Yeonsu Oh; Yooncheol Ha; Qwein Ahn; Sung Hoon Kim; Kyung Dong Cho; Bog Hieu Lee; Chanhee Chae

doi:10.1292/jvms.09-0308

Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs

Chung Hyun Kim, Yeonsu Oh, Yooncheol Ha, Qwein Ahn, Sung Hoon Kim, Kyung Dong Cho, Bog Hieu Lee, Chanhee Chae

Research output: Contribution to journal › Comment/debate

10 Citations (Scopus)

Abstract

The aim of this study was to determine the immunoexpression of mucins in jejunal and ileal villous epithelium using six anti-bodies against MUC1, MUC2, MUC4 MUC5AC, MUC5B and MUC6. The immunohistochemical score for MUC1 has significantly intense staining compared with MUC2 (P=0.008) and the immunohistochemical socre for MUC4 and MUC 6 has significantly intense staining compared with MUC2 (P=0.032) in ileal villous surface. The immunohistochemical score for MUC4 (P=0.008), MUC5AC (P=0.016) and MUC6 (P=0.016) in ileal villous surface has significantly intense staining compared with ileal cryptic surface. The results of this study demonstrated that six mucins gave distinctly different expression patterns throughout the 1 week-old porcine small intestinal tract.

Original language	English
Pages (from-to)	245-247
Number of pages	3
Journal	Journal of Veterinary Medical Science
Volume	72
Issue number	2
DOIs	https://doi.org/10.1292/jvms.09-0308
Publication status	Published - Feb 2010

Keywords

Intestine
Mucin
Swine

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10.1292/jvms.09-0308

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title = "Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs",

abstract = "The aim of this study was to determine the immunoexpression of mucins in jejunal and ileal villous epithelium using six anti-bodies against MUC1, MUC2, MUC4 MUC5AC, MUC5B and MUC6. The immunohistochemical score for MUC1 has significantly intense staining compared with MUC2 (P=0.008) and the immunohistochemical socre for MUC4 and MUC 6 has significantly intense staining compared with MUC2 (P=0.032) in ileal villous surface. The immunohistochemical score for MUC4 (P=0.008), MUC5AC (P=0.016) and MUC6 (P=0.016) in ileal villous surface has significantly intense staining compared with ileal cryptic surface. The results of this study demonstrated that six mucins gave distinctly different expression patterns throughout the 1 week-old porcine small intestinal tract.",

keywords = "Intestine, Mucin, Swine",

author = "Kim, {Chung Hyun} and Yeonsu Oh and Yooncheol Ha and Qwein Ahn and Kim, {Sung Hoon} and Cho, {Kyung Dong} and Lee, {Bog Hieu} and Chanhee Chae",

year = "2010",

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doi = "10.1292/jvms.09-0308",

language = "English",

volume = "72",

pages = "245--247",

journal = "Journal of Veterinary Medical Science",

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publisher = "Japanese Society of Veterinary Science",

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T1 - Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs

AU - Kim, Chung Hyun

AU - Oh, Yeonsu

AU - Ha, Yooncheol

AU - Ahn, Qwein

AU - Kim, Sung Hoon

AU - Cho, Kyung Dong

AU - Lee, Bog Hieu

AU - Chae, Chanhee

PY - 2010/2

Y1 - 2010/2

N2 - The aim of this study was to determine the immunoexpression of mucins in jejunal and ileal villous epithelium using six anti-bodies against MUC1, MUC2, MUC4 MUC5AC, MUC5B and MUC6. The immunohistochemical score for MUC1 has significantly intense staining compared with MUC2 (P=0.008) and the immunohistochemical socre for MUC4 and MUC 6 has significantly intense staining compared with MUC2 (P=0.032) in ileal villous surface. The immunohistochemical score for MUC4 (P=0.008), MUC5AC (P=0.016) and MUC6 (P=0.016) in ileal villous surface has significantly intense staining compared with ileal cryptic surface. The results of this study demonstrated that six mucins gave distinctly different expression patterns throughout the 1 week-old porcine small intestinal tract.

AB - The aim of this study was to determine the immunoexpression of mucins in jejunal and ileal villous epithelium using six anti-bodies against MUC1, MUC2, MUC4 MUC5AC, MUC5B and MUC6. The immunohistochemical score for MUC1 has significantly intense staining compared with MUC2 (P=0.008) and the immunohistochemical socre for MUC4 and MUC 6 has significantly intense staining compared with MUC2 (P=0.032) in ileal villous surface. The immunohistochemical score for MUC4 (P=0.008), MUC5AC (P=0.016) and MUC6 (P=0.016) in ileal villous surface has significantly intense staining compared with ileal cryptic surface. The results of this study demonstrated that six mucins gave distinctly different expression patterns throughout the 1 week-old porcine small intestinal tract.

KW - Intestine

KW - Mucin

KW - Swine

UR - http://www.scopus.com/inward/record.url?scp=77649295680&partnerID=8YFLogxK

U2 - 10.1292/jvms.09-0308

DO - 10.1292/jvms.09-0308

M3 - Comment/debate

C2 - 19942807

AN - SCOPUS:77649295680

SN - 0916-7250

VL - 72

SP - 245

EP - 247

JO - Journal of Veterinary Medical Science

JF - Journal of Veterinary Medical Science

IS - 2

ER -

Expression of mucins in the mucosal surface of small intestines in 1 week-old pigs

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Keywords

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