Abstract
Polymer micelles containing calcium phosphate (CaP) minerals on the shell domain were developed by nanotemplate-driven mineralization. The polymer micelle nanotemplate was prepared by self-assembly of a poly(ε-caprolactone)-b- poly(methacrylic acid) (PCL-b-PMAA) copolymer. PMAA formed the anionic outer shell, and PCL constructed the hydrophobic inner core. Subsequent addition of calcium and phosphate ions to micellar solutions induced CaP mineral deposition within the PMAA shell domain. Transmission electron microscopy (TEM) showed the well-defined nanostructure consisting of the CaP nanoshell and the PCL inner core. Energy-dispersive X-ray spectroscopy (EDS) confirmed CaP deposition on polymer micelles. Dynamic light scattering (DLS) study showed CaP mineralization greatly enhanced the micellar stability.
| Original language | English |
|---|---|
| Pages (from-to) | 743-752 |
| Number of pages | 10 |
| Journal | Polymer Bulletin |
| Volume | 65 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Oct 2010 |
Bibliographical note
Funding Information:This research was supported by a grant from “the fundamental R&D Program for Core Technology of Materials” funded by Ministry of Knowledge Economy, Republic of Korea (K0006028), and a Grant (code #: 2010K000296) from “Center for Nanostructured Materials Technology” under “21st Century Frontier R&D Programs” of the Ministry of Education, Science and Technology, Republic of Korea.
Keywords
- Calcium phosphate
- Mineralization
- Nanoparticles
- Polymer micelle