Fluorescent hydrogel fibers for long-term in vivo glucose monitoring

Y. J. Heo; H. Shibata; T. Okitsu; T. Kawanishi; S. Takeuchi

doi:10.1109/TRANSDUCERS.2011.5969342

Fluorescent hydrogel fibers for long-term in vivo glucose monitoring

Y. J. Heo, H. Shibata, T. Okitsu, T. Kawanishi, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

5 Citations (Scopus)

Abstract

Fluorescence-based implantable glucose sensors can provide continuous glucose monitoring (CGM) with wireless transdermal transmission and long-lasting activity in vivo. Here, we present a long-term in vivo glucose monitoring method using glucose-responsive fluorescent hydrogel fibers. The fiber structure enables the sensor to remain at an implantation site for a long period and be removed from the implantation site after use. We found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAAm) hydrogel fibers reduced inflammation, transdermally glowed and continuously responded to blood glucose concentration changes after 2.5 months, showing their potential application for long-term in vivo continuous glucose monitoring.

Original language	English
Title of host publication	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages	2140-2143
Number of pages	4
DOIs	https://doi.org/10.1109/TRANSDUCERS.2011.5969342
Publication status	Published - 2011
Event	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China Duration: 5 Jun 2011 → 9 Jun 2011

Publication series

Name	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Conference

Conference	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/Territory	China
City	Beijing
Period	5/06/11 → 9/06/11

Keywords

continuous glucose monitoring
glucose-responsive fluorescence
hydrogel fiber
long-term monitoring
polyethylene glycol

Access to Document

10.1109/TRANSDUCERS.2011.5969342

Cite this

Heo, Y. J., Shibata, H., Okitsu, T., Kawanishi, T., & Takeuchi, S. (2011). Fluorescent hydrogel fibers for long-term in vivo glucose monitoring. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 (pp. 2140-2143). Article 5969342 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). https://doi.org/10.1109/TRANSDUCERS.2011.5969342

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title = "Fluorescent hydrogel fibers for long-term in vivo glucose monitoring",

abstract = "Fluorescence-based implantable glucose sensors can provide continuous glucose monitoring (CGM) with wireless transdermal transmission and long-lasting activity in vivo. Here, we present a long-term in vivo glucose monitoring method using glucose-responsive fluorescent hydrogel fibers. The fiber structure enables the sensor to remain at an implantation site for a long period and be removed from the implantation site after use. We found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAAm) hydrogel fibers reduced inflammation, transdermally glowed and continuously responded to blood glucose concentration changes after 2.5 months, showing their potential application for long-term in vivo continuous glucose monitoring.",

keywords = "continuous glucose monitoring, glucose-responsive fluorescence, hydrogel fiber, long-term monitoring, polyethylene glycol",

author = "Heo, {Y. J.} and H. Shibata and T. Okitsu and T. Kawanishi and S. Takeuchi",

note = "Copyright: Copyright 2011 Elsevier B.V., All rights reserved.; 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 ; Conference date: 05-06-2011 Through 09-06-2011",

year = "2011",

doi = "10.1109/TRANSDUCERS.2011.5969342",

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series = "2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11",

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Heo, YJ, Shibata, H, Okitsu, T, Kawanishi, T & Takeuchi, S 2011, Fluorescent hydrogel fibers for long-term in vivo glucose monitoring. in 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11., 5969342, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, pp. 2140-2143, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, Beijing, China, 5/06/11. https://doi.org/10.1109/TRANSDUCERS.2011.5969342

Fluorescent hydrogel fibers for long-term in vivo glucose monitoring. / Heo, Y. J.; Shibata, H.; Okitsu, T. et al.
2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 2140-2143 5969342 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Shibata, H.

AU - Okitsu, T.

AU - Kawanishi, T.

AU - Takeuchi, S.

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N2 - Fluorescence-based implantable glucose sensors can provide continuous glucose monitoring (CGM) with wireless transdermal transmission and long-lasting activity in vivo. Here, we present a long-term in vivo glucose monitoring method using glucose-responsive fluorescent hydrogel fibers. The fiber structure enables the sensor to remain at an implantation site for a long period and be removed from the implantation site after use. We found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAAm) hydrogel fibers reduced inflammation, transdermally glowed and continuously responded to blood glucose concentration changes after 2.5 months, showing their potential application for long-term in vivo continuous glucose monitoring.

AB - Fluorescence-based implantable glucose sensors can provide continuous glucose monitoring (CGM) with wireless transdermal transmission and long-lasting activity in vivo. Here, we present a long-term in vivo glucose monitoring method using glucose-responsive fluorescent hydrogel fibers. The fiber structure enables the sensor to remain at an implantation site for a long period and be removed from the implantation site after use. We found that the polyethylene glycol (PEG)-bonded polyacrylamide (PAAm) hydrogel fibers reduced inflammation, transdermally glowed and continuously responded to blood glucose concentration changes after 2.5 months, showing their potential application for long-term in vivo continuous glucose monitoring.

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KW - glucose-responsive fluorescence

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Heo YJ, Shibata H, Okitsu T, Kawanishi T, Takeuchi S. Fluorescent hydrogel fibers for long-term in vivo glucose monitoring. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 2140-2143. 5969342. (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). doi: 10.1109/TRANSDUCERS.2011.5969342

Fluorescent hydrogel fibers for long-term in vivo glucose monitoring

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