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Fluorescent hydrophobic probes based on intramolecular charge transfer state for sensitive protein detection in solution

  • Hyunsook Jun
  • , Yeon Hong Soo
  • , Soo Yoon Seung
  • , Chulhun Kang
  • , Myungkoo Suh

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

New hydrophobic intramolecular charge transfer probes, comprising an aminostyryl and a cyanopyranyl moieties, were developed for sensitive protein quantification in solution. The probes exhibited dramatic increase of fluorescence quantum yields with accompanying blue-shift of the emission when bound to protein-sodium dodecyl sulfate (SDS) complexes. Using this emission enhancement, the synthesized probes were successfully applied for determining protein concentrations in solution.

Original languageEnglish
Pages (from-to)690-691
Number of pages2
JournalChemistry Letters
Volume33
Issue number6
DOIs
Publication statusPublished - 5 Jun 2004

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