Functional scaffolds of bicontinuous, thermoresponsive L3-phase silica/hydroxyapatite nanocomposites

Jeong Ho Chang; Moo Eon Park; Yongsoon Shin; Gregory J. Exarhos; Kyung Ja Kim; Sang Cheon Lee; Kyung Sik Oh

doi:10.1039/b609409k

Functional scaffolds of bicontinuous, thermoresponsive L₃-phase silica/hydroxyapatite nanocomposites

Jeong Ho Chang, Moo Eon Park, Yongsoon Shin, Gregory J. Exarhos, Kyung Ja Kim, Sang Cheon Lee, Kyung Sik Oh

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Silicified L₃-poly(N-isopropylacrylamide)/hydroxyapatite nanocomposites have been prepared by the integration of a thermosensitive polymer and heterogeneous continuity in a 3-D interconnected porous structure for highly controlled drug release without initial burst release during step-wise temperature changes, and the in-vitro cytotoxicity test for biocompatibility is demonstrated.

Original language	English
Pages (from-to)	238-242
Number of pages	5
Journal	Journal of Materials Chemistry
Volume	17
Issue number	3
DOIs	https://doi.org/10.1039/b609409k
Publication status	Published - 2007

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abstract = "Silicified L3-poly(N-isopropylacrylamide)/hydroxyapatite nanocomposites have been prepared by the integration of a thermosensitive polymer and heterogeneous continuity in a 3-D interconnected porous structure for highly controlled drug release without initial burst release during step-wise temperature changes, and the in-vitro cytotoxicity test for biocompatibility is demonstrated.",

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AU - Chang, Jeong Ho

AU - Park, Moo Eon

AU - Shin, Yongsoon

AU - Exarhos, Gregory J.

AU - Kim, Kyung Ja

AU - Lee, Sang Cheon

AU - Oh, Kyung Sik

PY - 2007

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N2 - Silicified L3-poly(N-isopropylacrylamide)/hydroxyapatite nanocomposites have been prepared by the integration of a thermosensitive polymer and heterogeneous continuity in a 3-D interconnected porous structure for highly controlled drug release without initial burst release during step-wise temperature changes, and the in-vitro cytotoxicity test for biocompatibility is demonstrated.

AB - Silicified L3-poly(N-isopropylacrylamide)/hydroxyapatite nanocomposites have been prepared by the integration of a thermosensitive polymer and heterogeneous continuity in a 3-D interconnected porous structure for highly controlled drug release without initial burst release during step-wise temperature changes, and the in-vitro cytotoxicity test for biocompatibility is demonstrated.

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EP - 242

JO - Journal of Materials Chemistry

JF - Journal of Materials Chemistry

IS - 3

ER -

Functional scaffolds of bicontinuous, thermoresponsive L₃-phase silica/hydroxyapatite nanocomposites

Abstract

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