TY - GEN
T1 - Future approaches to organ regeneration
T2 - Microscale environments, stem cell engineering, and self-assembly of living tissues
AU - Hacking, S. Adam
AU - Kachouie, Nezamoddin N.
AU - Lee, Won Gu
AU - Khademhosseini, Ali
PY - 2009
Y1 - 2009
N2 - A promising means to address the limited supply of donor tissue is through the generation of artificial organs consisting of cells and materials. Progress towards this goal is limited by three main obstacles namely the generation of a sufficient number of cells specific to the organ, the arrangement of these cells in a functional tissue architecture and the delivery of nutrients and removal of waste from the tissue mass. This chapter describes the emerging approaches that may be achieved by the control of stem cell differentiation, control of the local tissue environment on the microscale, and the generation of complex structures containing multiple cell types.
AB - A promising means to address the limited supply of donor tissue is through the generation of artificial organs consisting of cells and materials. Progress towards this goal is limited by three main obstacles namely the generation of a sufficient number of cells specific to the organ, the arrangement of these cells in a functional tissue architecture and the delivery of nutrients and removal of waste from the tissue mass. This chapter describes the emerging approaches that may be achieved by the control of stem cell differentiation, control of the local tissue environment on the microscale, and the generation of complex structures containing multiple cell types.
UR - http://www.scopus.com/inward/record.url?scp=71749108383&partnerID=8YFLogxK
U2 - 10.3233/978-1-60750-050-6-214
DO - 10.3233/978-1-60750-050-6-214
M3 - Conference contribution
C2 - 19745484
AN - SCOPUS:71749108383
SN - 9781607500506
T3 - Studies in Health Technology and Informatics
SP - 214
EP - 235
BT - Strategy for the Future of Health
PB - IOS Press
ER -