Ginseng and obesity: Observations from assorted perspectives

Fayeza Md Siraj, Yeon Ju Kim, Sathishkumar Natarajan, Seok Kyu Jung, Dong Uk Yang, Deok Chun Yang

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Ginseng is a well known herb used for various purposes that possesses many beneficial effects for the human body and aids in recovery or cure for several diseases. There has been much research and many clinical trials designed to ascertain what these beneficial effects are. Studies have investigated ginseng effects on diabetes, osteoporosis, the immune system, and many other diseases. Research has also shown ginseng to be effective as an antiobesity treatment. Ginsenoside components inhibit differentiation inducers in adipocyte tissues. This review summarizes the in vivo and in vitro effects of various ginseng crude extracts/ginsenosides on obesity via activation of AMPK- and/or cAMP-dependent pathways, which are networks of transcription factors through which PPARγ and cofactors operate. Additional proteins, markers, and pathways are suggested for which the effects of ginseng saponins may be promising.

Original languageEnglish
Pages (from-to)1007-1016
Number of pages10
JournalFood Science and Biotechnology
Volume23
Issue number4
DOIs
Publication statusPublished - Aug 2014

Keywords

  • Panax ginseng
  • adipocyte
  • ginsenosides
  • obesity

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