Ginseng and obesity: Observations from assorted perspectives

Fayeza Md Siraj; Yeon Ju Kim; Sathishkumar Natarajan; Seok Kyu Jung; Dong Uk Yang; Deok Chun Yang

doi:10.1007/s10068-014-0137-x

Ginseng and obesity: Observations from assorted perspectives

Fayeza Md Siraj, Yeon Ju Kim, Sathishkumar Natarajan, Seok Kyu Jung, Dong Uk Yang, Deok Chun Yang

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Ginseng is a well known herb used for various purposes that possesses many beneficial effects for the human body and aids in recovery or cure for several diseases. There has been much research and many clinical trials designed to ascertain what these beneficial effects are. Studies have investigated ginseng effects on diabetes, osteoporosis, the immune system, and many other diseases. Research has also shown ginseng to be effective as an antiobesity treatment. Ginsenoside components inhibit differentiation inducers in adipocyte tissues. This review summarizes the in vivo and in vitro effects of various ginseng crude extracts/ginsenosides on obesity via activation of AMPK- and/or cAMP-dependent pathways, which are networks of transcription factors through which PPARγ and cofactors operate. Additional proteins, markers, and pathways are suggested for which the effects of ginseng saponins may be promising.

Original language	English
Pages (from-to)	1007-1016
Number of pages	10
Journal	Food Science and Biotechnology
Volume	23
Issue number	4
DOIs	https://doi.org/10.1007/s10068-014-0137-x
Publication status	Published - Aug 2014

Keywords

Panax ginseng
adipocyte
ginsenosides
obesity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10068-014-0137-x

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title = "Ginseng and obesity: Observations from assorted perspectives",

abstract = "Ginseng is a well known herb used for various purposes that possesses many beneficial effects for the human body and aids in recovery or cure for several diseases. There has been much research and many clinical trials designed to ascertain what these beneficial effects are. Studies have investigated ginseng effects on diabetes, osteoporosis, the immune system, and many other diseases. Research has also shown ginseng to be effective as an antiobesity treatment. Ginsenoside components inhibit differentiation inducers in adipocyte tissues. This review summarizes the in vivo and in vitro effects of various ginseng crude extracts/ginsenosides on obesity via activation of AMPK- and/or cAMP-dependent pathways, which are networks of transcription factors through which PPARγ and cofactors operate. Additional proteins, markers, and pathways are suggested for which the effects of ginseng saponins may be promising.",

keywords = "Panax ginseng, adipocyte, ginsenosides, obesity",

author = "Siraj, {Fayeza Md} and Kim, {Yeon Ju} and Sathishkumar Natarajan and Jung, {Seok Kyu} and Yang, {Dong Uk} and Yang, {Deok Chun}",

note = "Funding Information: Acknowledgments This research was supported by a grant from Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (#313038-03-1-SB010).",

year = "2014",

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doi = "10.1007/s10068-014-0137-x",

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AU - Siraj, Fayeza Md

AU - Kim, Yeon Ju

AU - Natarajan, Sathishkumar

AU - Jung, Seok Kyu

AU - Yang, Dong Uk

AU - Yang, Deok Chun

N1 - Funding Information: Acknowledgments This research was supported by a grant from Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (#313038-03-1-SB010).

PY - 2014/8

Y1 - 2014/8

N2 - Ginseng is a well known herb used for various purposes that possesses many beneficial effects for the human body and aids in recovery or cure for several diseases. There has been much research and many clinical trials designed to ascertain what these beneficial effects are. Studies have investigated ginseng effects on diabetes, osteoporosis, the immune system, and many other diseases. Research has also shown ginseng to be effective as an antiobesity treatment. Ginsenoside components inhibit differentiation inducers in adipocyte tissues. This review summarizes the in vivo and in vitro effects of various ginseng crude extracts/ginsenosides on obesity via activation of AMPK- and/or cAMP-dependent pathways, which are networks of transcription factors through which PPARγ and cofactors operate. Additional proteins, markers, and pathways are suggested for which the effects of ginseng saponins may be promising.

AB - Ginseng is a well known herb used for various purposes that possesses many beneficial effects for the human body and aids in recovery or cure for several diseases. There has been much research and many clinical trials designed to ascertain what these beneficial effects are. Studies have investigated ginseng effects on diabetes, osteoporosis, the immune system, and many other diseases. Research has also shown ginseng to be effective as an antiobesity treatment. Ginsenoside components inhibit differentiation inducers in adipocyte tissues. This review summarizes the in vivo and in vitro effects of various ginseng crude extracts/ginsenosides on obesity via activation of AMPK- and/or cAMP-dependent pathways, which are networks of transcription factors through which PPARγ and cofactors operate. Additional proteins, markers, and pathways are suggested for which the effects of ginseng saponins may be promising.

KW - Panax ginseng

KW - adipocyte

KW - ginsenosides

KW - obesity

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DO - 10.1007/s10068-014-0137-x

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JO - Food Science and Biotechnology

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SN - 1226-7708

IS - 4

ER -

Ginseng and obesity: Observations from assorted perspectives

Abstract

Keywords

UN SDGs

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