Graphene-Based Electrochemical Biosensors for Breast Cancer Detection

Ali Mohammadpour-Haratbar, Seyyed Behnam Abdollahi Boraei, Yasser Zare, Kyong Yop Rhee, Soo Jin Park

Research output: Contribution to journalReview articlepeer-review

30 Citations (Scopus)

Abstract

Breast cancer (BC) is the most common cancer in women, which is also the second most public cancer worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond the breast. In recent years, various BC biosensor strategies have been studied, including optical, electrical, electrochemical, and mechanical biosensors. In particular, the high sensitivity and short detection time of electrochemical biosensors make them suitable for the recognition of BC biomarkers. Moreover, the sensitivity of the electrochemical biosensor can be increased by incorporating nanomaterials. In this respect, the outstanding mechanical and electrical performances of graphene have led to an increasingly intense study of graphene-based materials for BC electrochemical biosensors. Hence, the present review examines the latest advances in graphene-based electrochemical biosensors for BC biosensing. For each biosensor, the detection limit (LOD), linear range (LR), and diagnosis technique are analyzed. This is followed by a discussion of the prospects and current challenges, along with potential strategies for enhancing the performance of electrochemical biosensors.

Original languageEnglish
Article number80
JournalBiosensors
Volume13
Issue number1
DOIs
Publication statusPublished - Jan 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

  • biomarker
  • breast cancer
  • electrochemical biosensors
  • graphene
  • nanoparticles

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