Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population

H. Gu; K. Kimm; Jong Keul Lee; Bermseok Oh

doi:10.1111/j.1399-0039.2005.00397.x

Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population

H. Gu, K. Kimm, Jong Keul Lee, Bermseok Oh

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

The polymorphism of HLA class II genes is largely confined to the exon 2 region. Sequence analysis of exon 2 of the DQB1 gene revealed the novel polymorphism in the Korean population. The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG→GGG), corresponding to non-synonymous amino acid change (Glu→Gly).

Original language	English
Pages (from-to)	503-504
Number of pages	2
Journal	Tissue Antigens
Volume	65
Issue number	5
DOIs	https://doi.org/10.1111/j.1399-0039.2005.00397.x
Publication status	Published - May 2005

Keywords

HLA-DQB1*0314
Korean
New allele
Sequence-based typing

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10.1111/j.1399-0039.2005.00397.x

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abstract = "The polymorphism of HLA class II genes is largely confined to the exon 2 region. Sequence analysis of exon 2 of the DQB1 gene revealed the novel polymorphism in the Korean population. The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG→GGG), corresponding to non-synonymous amino acid change (Glu→Gly).",

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AU - Lee, Jong Keul

AU - Oh, Bermseok

PY - 2005/5

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AB - The polymorphism of HLA class II genes is largely confined to the exon 2 region. Sequence analysis of exon 2 of the DQB1 gene revealed the novel polymorphism in the Korean population. The new DQB1 allele, DQB1*0314, was differed from DQB1*0304 only at codon 46 (GAG→GGG), corresponding to non-synonymous amino acid change (Glu→Gly).

KW - HLA-DQB10314

KW - Korean

KW - New allele

KW - Sequence-based typing

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IS - 5

ER -

Identification of a novel HLA-DQB1 allele, DQB1*0314, by sequence-based typing in the Korean population

Abstract

Keywords

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