@inproceedings{e5d10e64caa74c25a22e74e9fd349e35,
title = "Implantable hydrogel microfiber encapsulating pancreatic beta-cells for diabetes treatment",
abstract = "This paper describes implantable hydrogel microfibers encapsulating living pancreatic beta-cells for diabetes treatment. The structure of microfiber has a potential not only to implant but also to remove the pancreatic beta-cells encapsulated in the microfiber, indicating that our microfiber can be a cartridge-type device to regulate blood glucose. We successfully validated the potency of our microfibers by implanting them into chemically induced diabetic mice and normalizing their blood glucose. We believe that our method to encapsulate pancreatic beta-cells in the microfibers could be useful for cell-based medicine targeted to diabetes mellitus.",
keywords = "Cell encapsulation, Diabetes treatment, Pancreatic beta-cells, Tissue engineering",
author = "S. Sugimoto and Heo, {Y. J.} and H. Onoe and T. Okitsu and H. Kotera and S. Takeuchi",
note = "Copyright: Copyright 2013 Elsevier B.V., All rights reserved.; 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 ; Conference date: 02-10-2011 Through 06-10-2011",
year = "2011",
language = "English",
isbn = "9781618395955",
series = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
pages = "1248--1250",
booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",
}
