Abstract
The efficacy of Aster sphathulifolius (AS) for evaluation of preventive potencies against diabetes and diabetic complications was analyzed by assessment of inhibitory effects against advanced glycation end-products (AGEs) formation, rat lens aldose reductase (RLAR), α-glucosidase activity, and scavenging effects against DPPH. The 50% ethanol extract showed the highest DPPH radical scavenging activity (82.38%) at a concentration of 100 μg/mL, exhibited the most potent AGEs formation inhibitory effect (93.88%) at a concentration of 200 μg/mL, showed the most potent RLAR inhibitory effect (86.44%) at a concentration of 11.11 μg/mL. The 95% ethanol extract showed a potent α-glucosidase inhibitory activity (19.16%) at a concentration of 1 mg/mL. The 50% ethanol extract value was 16.79%. The 50% ethanol extract exhibited the most potent antioxidant and preventive actions against diabetes and diabetic complications and can, thus, be a source of valuable compounds for prevention of diabetes and diabetic complications.
| Original language | English |
|---|---|
| Pages (from-to) | 301-306 |
| Number of pages | 6 |
| Journal | Food Science and Biotechnology |
| Volume | 24 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 2015 |
Bibliographical note
Publisher Copyright:© 2015, The Korean Society of Food Science and Technology and Springer Science+Business Media Dordrecht.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Aster sphathulifolius
- DPPH
- advanced glycation end-products
- rat lens aldose reductase
- α-glucosidase
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