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Isolation and characterization of the gene encoding the Drosophila melanogaster transcriptional elongation factor, TFIIS

  • Younsang Oh
  • , Jaeseung Yoon
  • , Kwanghee Baek

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

We have characterized a genomic clone encoding the Drosophila melanogaster transcriptional elongation factor, TFIIS. The coding region of the TFIIS gene is interrupted by a short intron. The potential promoter region, deduced from the determination of the transcription start point (tsp), lacks distinct TATAAA or CCAAT box consensus sequences. Southern analysis and the in situ hybridization to chromosomes suggests that it is single-copy gene which is localized to the 35B region on the left arm of the second chromosome.

Original languageEnglish
Pages (from-to)99-103
Number of pages5
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1262
Issue number1
DOIs
Publication statusPublished - 17 May 1995

Bibliographical note

Funding Information:
This work was supported by the Genetic Engineering Research grant from Korea Ministry of Education in 1993.

Keywords

  • (D. melanogaster)
  • Gene characterization
  • Genomic clone
  • Transcriptional elongation factor

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