@inproceedings{41c3162e7eda4814aa36726a488087cb,
title = "Large volume sample-pretreatment microdevice based on sol-gel 3D matrix",
abstract = "Sample-pretreatment is of great interest for micro-total-analysis-system due to the needs of relevant sample concentration and separation techniques for efficient detection. In this study, we demonstrated a novel 3-dimensional sol-gel matrix based microdevice that can process a large volume of the sample and capture target cells with magnetic nanoparticles (MNPs)-mediated colorimetric signal. The antibody-MNP-DNA-Photocleavable linker complexes were immobilized on the sol-gel and the capture was enhanced by 3D matrix and flutter pumping scheme. The concentrated cells were released after UV irradiation, and analyzed based on MNP-mediated colorimetric detection. This novel platform suggests a simple biosensor device with sample-in-answer-out capability.",
keywords = "Colorimetric detection, Microfluidic, Sample-pretreatment, Sol-gel",
author = "Jung, {J. H.} and Lee, {C. J.} and Woo, {M. A.} and Kim, {M. I.} and Park, {H. G.} and Seo, {T. S.}",
year = "2010",
language = "English",
isbn = "9781618390622",
series = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
pages = "333--335",
booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010",
note = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 ; Conference date: 03-10-2010 Through 07-10-2010",
}