Abstract
Metabolomics is a high throughput analytical technique used to globally measure low molecular weight metabolites, allowing simultaneous metabolic comparison of different biological samples and thus highlighting differentially produced compounds as potential biomarkers. Although microbes are renowned as prolific sources of antibiotics, the traditional approach for new anti-infectives discovery is time-consuming and labor-intensive. In this review, the use of NMR- or MS-based metabolomics is proposed as an efficient approach to find antimicrobials in microbial single- or co-cultures.
Original language | English |
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Pages (from-to) | 11-17 |
Number of pages | 7 |
Journal | Drug Discovery Today: Technologies |
Volume | 13 |
DOIs | |
Publication status | Published - 1 Jun 2015 |
Bibliographical note
Publisher Copyright:© 2015 Elsevier Ltd.