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Multidetector computed tomography findings and correlations with proteinuria in nutcracker syndrome

  • Byoung Soo Cho
  • , Jin Soon Suh
  • , Won Ho Hahn
  • , Sung Do Kim
  • , Joo Won Lim

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

syndrome (NS) and its associationwith proteinuria. The angle and distance between the aorta and the superior mesenteric artery (SMA), the degree of difference in corticomedullary enhancement (DCE) between kidneys in the nephrographic phase of computed tomography, peak velocity ratio (PVR), and anteroposterior diameter ratio (APDR) in the sonogram were measured. The MDCT results, sonogram results, and the ratio of protein:creatinine were significantly different between NS patients and the controls. The area under the curve for angle, distance, and DCE were 0.895±0.058, 0.876±0.063, and 0.942±0.036, respectively. The cutoff values for angle and distance had sensitivity and specificity values of 96.2 and 80% for <22.4° and 84.6 and 80% for <4.9 mm, respectively. The DCE had a sensitivity of 88.5% and a specificity of 100% for the positive scores. There were significant correlations between the degree of DCE and the ratio of protein:creatinine (r=0.337, p=0.031), and between distance and the ratio of protein:creatinine (r=-0.419, p= 0.006). We conclude that MDCT has diagnostic value for NS in children and that MDCT findings are correlated with proteinuria.

Original languageEnglish
Pages (from-to)469-475
Number of pages7
JournalPediatric Nephrology
Volume25
Issue number3
DOIs
Publication statusPublished - Mar 2010

Bibliographical note

Funding Information:
This research was supported by a grant KHU-20081244 from Kyung Hee University program For the Young Researcher in Medical Science.

Keywords

  • Children
  • MDCT
  • Nutcracker syndrome
  • Orthostatic proteinuria

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