Nano/Microfluidics for diagnosis of infectious diseases in developing countries

Won Gu Lee, Yun Gon Kim, Bong Geun Chung, Utkan Demirci, Ali Khademhosseini

Research output: Contribution to journalReview articlepeer-review

314 Citations (Scopus)

Abstract

Nano/Microfluidic technologies are emerging as powerful enabling tools for diagnosis and monitoring of infectious diseases in both developed and developing countries. Miniaturized nano/microfluidic platforms that precisely manipulate small fluid volumes can be used to enable medical diagnosis in a more rapid and accurate manner. In particular, these nano/microfluidic diagnostic technologies are potentially applicable to global health applications, since they are disposable, inexpensive, portable, and easy-to-use for detection of infectious diseases. In this paper, we review recent advances in nano/microfluidic technologies for clinical point-of-care applications at resource-limited settings in developing countries.

Original languageEnglish
Pages (from-to)449-457
Number of pages9
JournalAdvanced Drug Delivery Reviews
Volume62
Issue number4-5
DOIs
Publication statusPublished - 18 Mar 2010

Bibliographical note

Funding Information:
This work was supported by the National Institute of Health by grants ( EB007249 , DE019024 , HL092836 , and AI081534 ). W. G. Lee was partially supported by the Korea Research Foundation Grant funded by the Korean Government (MOEHRD) ( KRF-2007-357-D00035 ).

Keywords

  • Diagnostics
  • Global health
  • HIV/AIDS
  • Infectious diseases
  • Nano/Microfluidics
  • Point-of-care

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