NMR-based plant metabolomics: Where do we stand, where do we go?

Hye Kyong Kim; Young Hae Choi; Robert Verpoorte

doi:10.1016/j.tibtech.2011.02.001

NMR-based plant metabolomics: Where do we stand, where do we go?

Hye Kyong Kim, Young Hae Choi, Robert Verpoorte

Research output: Contribution to journal › Review article › peer-review

345 Citations (Scopus)

Abstract

NMR-based metabolomics is an important tool for studying biological systems and has been applied in various organisms, including animals, plants and microbes. NMR is able to provide a 'holistic view' of the metabolites under certain conditions, and thus is advantageous for metabolomic studies. To maximize the use of the information obtained, it is also important to create a platform to measure, store and share data. Public databases for storing and sharing information are still lacking for NMR-based metabolomic analysis in plants. Such databases are urgently needed to make metabolic profiling a real omics technology. In addition, to understand metabolic processes in depth, single-cell analysis and the turnover of metabolites in pathways (fluxomics) should be measured.

Original language	English
Pages (from-to)	267-275
Number of pages	9
Journal	Trends in Biotechnology
Volume	29
Issue number	6
DOIs	https://doi.org/10.1016/j.tibtech.2011.02.001
Publication status	Published - Jun 2011

Bibliographical note

Funding Information:
The authors thank Ms. E.G. Wilson for her comments and review of the manuscript. Financial support from STW Genbiotics (Project No. 10467, GENEXPAND to H.K. Kim) and the Nederlands Genomics Initiative (Horizon Project No. 93519012 to Y.H. Choi) is greatly appreciated.

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title = "NMR-based plant metabolomics: Where do we stand, where do we go?",

abstract = "NMR-based metabolomics is an important tool for studying biological systems and has been applied in various organisms, including animals, plants and microbes. NMR is able to provide a 'holistic view' of the metabolites under certain conditions, and thus is advantageous for metabolomic studies. To maximize the use of the information obtained, it is also important to create a platform to measure, store and share data. Public databases for storing and sharing information are still lacking for NMR-based metabolomic analysis in plants. Such databases are urgently needed to make metabolic profiling a real omics technology. In addition, to understand metabolic processes in depth, single-cell analysis and the turnover of metabolites in pathways (fluxomics) should be measured.",

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note = "Funding Information: The authors thank Ms. E.G. Wilson for her comments and review of the manuscript. Financial support from STW Genbiotics (Project No. 10467, GENEXPAND to H.K. Kim) and the Nederlands Genomics Initiative (Horizon Project No. 93519012 to Y.H. Choi) is greatly appreciated.",

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AU - Verpoorte, Robert

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NMR-based plant metabolomics: Where do we stand, where do we go?

Abstract

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