Over a decade of progress: Crystallization in microfluidic systems

Jiye Jang; Woo Sik Kim; Tae Seok Seo; Bum Jun Park

doi:10.1016/j.cej.2024.153657

Over a decade of progress: Crystallization in microfluidic systems

Jiye Jang, Woo Sik Kim, Tae Seok Seo, Bum Jun Park

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

This review explores recent advancements in microfluidic crystallization that use the synergy of miniaturization technologies and fluid dynamics to enhance precision and control in crystal formation. Focusing on crystallization methodologies such as antisolvent use, evaporation, temperature control, diffusion, spray drying, seeding, and the application of external sources, we highlight how microfluidic systems facilitate the synthesis of crystals with engineered morphologies, sizes, and properties. By emphasizing the benefits of cost-effectiveness, enhanced heat and mass transfer, and integration with real-time monitoring and analytical tools, this paper offers a comprehensive overview of the impactful contributions of microfluidic technologies to crystallization research and discusses potential future developments in this field.

Original language	English
Article number	153657
Journal	Chemical Engineering Journal
Volume	495
DOIs	https://doi.org/10.1016/j.cej.2024.153657
Publication status	Published - 1 Sept 2024

Bibliographical note

Publisher Copyright:
© 2024 Elsevier B.V.

Keywords

Crystallization
Crystallization driving force
Fluid dynamics
Microfluidics
Miniaturization

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10.1016/j.cej.2024.153657

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title = "Over a decade of progress: Crystallization in microfluidic systems",

abstract = "This review explores recent advancements in microfluidic crystallization that use the synergy of miniaturization technologies and fluid dynamics to enhance precision and control in crystal formation. Focusing on crystallization methodologies such as antisolvent use, evaporation, temperature control, diffusion, spray drying, seeding, and the application of external sources, we highlight how microfluidic systems facilitate the synthesis of crystals with engineered morphologies, sizes, and properties. By emphasizing the benefits of cost-effectiveness, enhanced heat and mass transfer, and integration with real-time monitoring and analytical tools, this paper offers a comprehensive overview of the impactful contributions of microfluidic technologies to crystallization research and discusses potential future developments in this field.",

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AU - Seo, Tae Seok

AU - Park, Bum Jun

PY - 2024/9/1

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AB - This review explores recent advancements in microfluidic crystallization that use the synergy of miniaturization technologies and fluid dynamics to enhance precision and control in crystal formation. Focusing on crystallization methodologies such as antisolvent use, evaporation, temperature control, diffusion, spray drying, seeding, and the application of external sources, we highlight how microfluidic systems facilitate the synthesis of crystals with engineered morphologies, sizes, and properties. By emphasizing the benefits of cost-effectiveness, enhanced heat and mass transfer, and integration with real-time monitoring and analytical tools, this paper offers a comprehensive overview of the impactful contributions of microfluidic technologies to crystallization research and discusses potential future developments in this field.

KW - Crystallization

KW - Crystallization driving force

KW - Fluid dynamics

KW - Microfluidics

KW - Miniaturization

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VL - 495

JO - Chemical Engineering Journal

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Over a decade of progress: Crystallization in microfluidic systems

Abstract

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Keywords

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