pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Gyu Ha Hwang; Kyung Hyun Min; Hong Jae Lee; Hye Young Nam; Gi Hyun Choi; Byung Joo Kim; Seo Young Jeong; Sang Cheon Lee

doi:10.1039/c4cc01584c

pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Gyu Ha Hwang, Kyung Hyun Min, Hong Jae Lee, Hye Young Nam, Gi Hyun Choi, Byung Joo Kim, Seo Young Jeong, Sang Cheon Lee

Research output: Contribution to journal › Article › peer-review

54 Citations (Scopus)

Abstract

We report on pH-responsive core-shell polymer micelles with catechol-Fe³⁺ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

Original language	English
Pages (from-to)	4351-4353
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	33
DOIs	https://doi.org/10.1039/c4cc01584c
Publication status	Published - 27 Mar 2014

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title = "pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links",

abstract = "We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.",

author = "Hwang, {Gyu Ha} and Min, {Kyung Hyun} and Lee, {Hong Jae} and Nam, {Hye Young} and Choi, {Gi Hyun} and Kim, {Byung Joo} and Jeong, {Seo Young} and Lee, {Sang Cheon}",

year = "2014",

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doi = "10.1039/c4cc01584c",

language = "English",

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journal = "Chemical Communications",

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T1 - pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

AU - Hwang, Gyu Ha

AU - Min, Kyung Hyun

AU - Lee, Hong Jae

AU - Nam, Hye Young

AU - Choi, Gi Hyun

AU - Kim, Byung Joo

AU - Jeong, Seo Young

AU - Lee, Sang Cheon

PY - 2014/3/27

Y1 - 2014/3/27

N2 - We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

AB - We report on pH-responsive core-shell polymer micelles with catechol-Fe3+ coordinated core cross-links, which provide robustness to drug-loaded polymer micelles and allow the facilitated intracellular release of loaded anticancer drugs in response to an endosomal acidic pH.

UR - http://www.scopus.com/inward/record.url?scp=84897132086&partnerID=8YFLogxK

U2 - 10.1039/c4cc01584c

DO - 10.1039/c4cc01584c

M3 - Article

C2 - 24643304

AN - SCOPUS:84897132086

SN - 1359-7345

VL - 50

SP - 4351

EP - 4353

JO - Chemical Communications

JF - Chemical Communications

IS - 33

ER -

pH-Responsive robust polymer micelles with metal-ligand coordinated core cross-links

Abstract

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