Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications

Donghyun Lee; Sang Jin Lee; Ji Hoi Moon; Joo Hyoung Kim; Dong Nyoung Heo; Jae Beum Bang; Ho Nam Lim; Il Keun Kwon

doi:10.1016/j.jiec.2018.05.030

Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications

Donghyun Lee, Sang Jin Lee, Ji Hoi Moon, Joo Hyoung Kim, Dong Nyoung Heo, Jae Beum Bang, Ho Nam Lim, Il Keun Kwon

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Abstract

The materials of the dental barrier membranes (DBM), which is widely used for effective alveolar bone reconstruction, require high biocompatibility and additional functions. In this study, we prepared a chitosan/polyurethane (CSP) nanofibrous membrane incorporated silver nanoparticles (AgNPs) within the membrane. Characterization of CS-AgNP/polyurethane composite (AgCSP) nanofiber membranes showed that AgNPs were well embedded in chitosan membranes. In addition, biocompatibility and antibacterial effect against Porphyromonas gingivalis of the AgCSP was demonstrated by viability analysis and growth inhibition test. Collectively, AgCSP nanofiber membrane with antibacterial activity as well as biocompatibility may be useful in DBM and other tissue engineering applications.

Original language	English
Pages (from-to)	196-202
Number of pages	7
Journal	Journal of Industrial and Engineering Chemistry
Volume	66
DOIs	https://doi.org/10.1016/j.jiec.2018.05.030
Publication status	Published - 25 Oct 2018

Bibliographical note

Publisher Copyright:
© 2018 The Korean Society of Industrial and Engineering Chemistry

Keywords

Antibacterial activity
Chitosan nanofiber
Electrospinning
Silver nanoparticle

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10.1016/j.jiec.2018.05.030

Cite this

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title = "Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications",

abstract = "The materials of the dental barrier membranes (DBM), which is widely used for effective alveolar bone reconstruction, require high biocompatibility and additional functions. In this study, we prepared a chitosan/polyurethane (CSP) nanofibrous membrane incorporated silver nanoparticles (AgNPs) within the membrane. Characterization of CS-AgNP/polyurethane composite (AgCSP) nanofiber membranes showed that AgNPs were well embedded in chitosan membranes. In addition, biocompatibility and antibacterial effect against Porphyromonas gingivalis of the AgCSP was demonstrated by viability analysis and growth inhibition test. Collectively, AgCSP nanofiber membrane with antibacterial activity as well as biocompatibility may be useful in DBM and other tissue engineering applications.",

keywords = "Antibacterial activity, Chitosan nanofiber, Electrospinning, Silver nanoparticle",

author = "Donghyun Lee and Lee, \{Sang Jin\} and Moon, \{Ji Hoi\} and Kim, \{Joo Hyoung\} and Heo, \{Dong Nyoung\} and Bang, \{Jae Beum\} and Lim, \{Ho Nam\} and Kwon, \{Il Keun\}",

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year = "2018",

month = oct,

day = "25",

doi = "10.1016/j.jiec.2018.05.030",

language = "English",

volume = "66",

pages = "196--202",

journal = "Journal of Industrial and Engineering Chemistry",

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publisher = "Korean Society of Industrial Engineering Chemistry",

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TY - JOUR

T1 - Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications

AU - Lee, Donghyun

AU - Lee, Sang Jin

AU - Moon, Ji Hoi

AU - Kim, Joo Hyoung

AU - Heo, Dong Nyoung

AU - Bang, Jae Beum

AU - Lim, Ho Nam

AU - Kwon, Il Keun

PY - 2018/10/25

Y1 - 2018/10/25

N2 - The materials of the dental barrier membranes (DBM), which is widely used for effective alveolar bone reconstruction, require high biocompatibility and additional functions. In this study, we prepared a chitosan/polyurethane (CSP) nanofibrous membrane incorporated silver nanoparticles (AgNPs) within the membrane. Characterization of CS-AgNP/polyurethane composite (AgCSP) nanofiber membranes showed that AgNPs were well embedded in chitosan membranes. In addition, biocompatibility and antibacterial effect against Porphyromonas gingivalis of the AgCSP was demonstrated by viability analysis and growth inhibition test. Collectively, AgCSP nanofiber membrane with antibacterial activity as well as biocompatibility may be useful in DBM and other tissue engineering applications.

AB - The materials of the dental barrier membranes (DBM), which is widely used for effective alveolar bone reconstruction, require high biocompatibility and additional functions. In this study, we prepared a chitosan/polyurethane (CSP) nanofibrous membrane incorporated silver nanoparticles (AgNPs) within the membrane. Characterization of CS-AgNP/polyurethane composite (AgCSP) nanofiber membranes showed that AgNPs were well embedded in chitosan membranes. In addition, biocompatibility and antibacterial effect against Porphyromonas gingivalis of the AgCSP was demonstrated by viability analysis and growth inhibition test. Collectively, AgCSP nanofiber membrane with antibacterial activity as well as biocompatibility may be useful in DBM and other tissue engineering applications.

KW - Antibacterial activity

KW - Chitosan nanofiber

KW - Electrospinning

KW - Silver nanoparticle

UR - https://www.scopus.com/pages/publications/85048867020

U2 - 10.1016/j.jiec.2018.05.030

DO - 10.1016/j.jiec.2018.05.030

M3 - Article

AN - SCOPUS:85048867020

SN - 1226-086X

VL - 66

SP - 196

EP - 202

JO - Journal of Industrial and Engineering Chemistry

JF - Journal of Industrial and Engineering Chemistry

ER -

Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications

Abstract

Bibliographical note

Keywords

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