TY - JOUR
T1 - Radiosurgical considerations for cavernous sinus hemangioma
T2 - long-term clinical outcomes
AU - Park, Chang Kyu
AU - Choi, Seok Keun
AU - Kang, Il Ho
AU - Choi, Man Kyu
AU - Park, Bong Jin
AU - Lim, Young Jin
N1 - Publisher Copyright:
© 2015, Springer-Verlag Wien.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Background: Cavernous hemangiomas are rare vascular tumors in the cavernous sinus. Cranial neuropathies induced by cavernous sinus hemangiomas (CSH) necessitate tumor reduction, but surgery is extremely difficult due to the abundant vascularization of the lesion. We studied the effectiveness and safety of Gamma Knife radiosurgery (GKRS) for CSH. Methods: We performed a retrospective analysis of 25 patients with CSH who were treated by GKRS between March 1992 and December 2014. Age, sex, target volume, and irradiation dose were analyzed as prognostic factors for CSH treated by GKRS. Results: Eleven (84.6 %) patients had tumor shrinkage within 12 months after GKRS. Two patients experienced tumor progression, but tumor size decreased over 2 years after GKRS. No patients had permanent complications, and all patients experienced symptomatic improvement. There were no significant factors that predicted the prognosis of CSH. Conclusions: The optimal treatment for CSH has been unclear; however, in this study, GKRS was an effective and safe treatment for CSH. Thus, GKRS may be a primary treatment for CSHs in high-risk surgery patients.
AB - Background: Cavernous hemangiomas are rare vascular tumors in the cavernous sinus. Cranial neuropathies induced by cavernous sinus hemangiomas (CSH) necessitate tumor reduction, but surgery is extremely difficult due to the abundant vascularization of the lesion. We studied the effectiveness and safety of Gamma Knife radiosurgery (GKRS) for CSH. Methods: We performed a retrospective analysis of 25 patients with CSH who were treated by GKRS between March 1992 and December 2014. Age, sex, target volume, and irradiation dose were analyzed as prognostic factors for CSH treated by GKRS. Results: Eleven (84.6 %) patients had tumor shrinkage within 12 months after GKRS. Two patients experienced tumor progression, but tumor size decreased over 2 years after GKRS. No patients had permanent complications, and all patients experienced symptomatic improvement. There were no significant factors that predicted the prognosis of CSH. Conclusions: The optimal treatment for CSH has been unclear; however, in this study, GKRS was an effective and safe treatment for CSH. Thus, GKRS may be a primary treatment for CSHs in high-risk surgery patients.
KW - Cavernous sinus
KW - Gamma Knife radiosurgery
KW - Hemangioma
UR - http://www.scopus.com/inward/record.url?scp=84954363502&partnerID=8YFLogxK
U2 - 10.1007/s00701-015-2657-4
DO - 10.1007/s00701-015-2657-4
M3 - Article
C2 - 26658989
AN - SCOPUS:84954363502
SN - 0001-6268
VL - 158
SP - 313
EP - 318
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
IS - 2
ER -