Reaction-based two-photon probes for mercury ions: Fluorescence imaging with dual optical windows

Alla Sreenivasa Rao; Dokyoung Kim; Taejun Wang; Ki Hean Kim; Sekyu Hwang; Kyo Han Ahn

doi:10.1021/ol3009057

Reaction-based two-photon probes for mercury ions: Fluorescence imaging with dual optical windows

Alla Sreenivasa Rao
, Dokyoung Kim
, Taejun Wang
, Ki Hean Kim
, Sekyu Hwang
, Kyo Han Ahn

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Abstract

For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.

Original language	English
Pages (from-to)	2598-2601
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	10
DOIs	https://doi.org/10.1021/ol3009057
Publication status	Published - 18 May 2012

Access to Document

10.1021/ol3009057

Cite this

@article{0f66d14c76944cfbadc7a1eddd802842,

title = "Reaction-based two-photon probes for mercury ions: Fluorescence imaging with dual optical windows",

abstract = "For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.",

author = "Rao, \{Alla Sreenivasa\} and Dokyoung Kim and Taejun Wang and Kim, \{Ki Hean\} and Sekyu Hwang and Ahn, \{Kyo Han\}",

year = "2012",

month = may,

day = "18",

doi = "10.1021/ol3009057",

language = "English",

volume = "14",

pages = "2598--2601",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "10",

}

TY - JOUR

T1 - Reaction-based two-photon probes for mercury ions

T2 - Fluorescence imaging with dual optical windows

AU - Rao, Alla Sreenivasa

AU - Kim, Dokyoung

AU - Wang, Taejun

AU - Kim, Ki Hean

AU - Hwang, Sekyu

AU - Ahn, Kyo Han

PY - 2012/5/18

Y1 - 2012/5/18

N2 - For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.

AB - For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.

UR - https://www.scopus.com/pages/publications/84862065395

U2 - 10.1021/ol3009057

DO - 10.1021/ol3009057

M3 - Article

C2 - 22564078

AN - SCOPUS:84862065395

SN - 1523-7060

VL - 14

SP - 2598

EP - 2601

JO - Organic Letters

JF - Organic Letters

IS - 10

ER -

Reaction-based two-photon probes for mercury ions: Fluorescence imaging with dual optical windows

Abstract

Access to Document

Other files and links

Fingerprint

Cite this