Real world epidemiology of myeloproliferative neoplasms: a population based study in Korea 2004–2013

Ja Min Byun, Young Jin Kim, Taemi Youk, John Jeongseok Yang, Jongha Yoo, Tae Sung Park

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Myeloproliferative neoplasms (MPNs), with an expected increment in number, impose substantial economic and social burdens. To this end, we conducted a nationwide population-based descriptive epidemiology study. We also investigated medical cost associated with MPNs. Prevalence was the highest for essential thrombocythemia (ET) (range 4.1–9.0 per 100,000), followed by polycythemia vera (PV) (range 2.8–5.4 per 100,000) and primary myelofibrosis (PMF) (range 0.5–0.9 per 100,000). ET incurred the highest cumulative total cost at US$35 million and the most frequent hospital visits, while PMF incurred the highest average cost per person at US$5000. The mean hemoglobin level was 16.9 ± 2.2 g/dL for PV males and 15.5 ± 2.7 g/dL for PV females. Further analyses on hemoglobin levels showed the true positive rate of PV from the significantly elevated hemoglobin group (defined as >18.5 g/dL for men and >16.5 g/dL for women) was 3.01% and that of MPNs was 3.1%. Here, we provide the biggest population-based report on MPN epidemiology that can readily be used as a representative Asian data.

Original languageEnglish
Pages (from-to)373-381
Number of pages9
JournalAnnals of Hematology
Volume96
Issue number3
DOIs
Publication statusPublished - 1 Mar 2017

Bibliographical note

Publisher Copyright:
© 2016, Springer-Verlag Berlin Heidelberg.

Keywords

  • Asia
  • Epidemiology
  • Medical cost
  • Myeloproliferative neoplasm

Fingerprint

Dive into the research topics of 'Real world epidemiology of myeloproliferative neoplasms: a population based study in Korea 2004–2013'. Together they form a unique fingerprint.

Cite this