Synthesis and evaluation of lasonolide a analogues

Jung Min Joo; Hyo Shin Kwak; Jin Hyun Park; Ho Young Song; Eun Lee

doi:10.1016/j.bmcl.2004.01.088

Synthesis and evaluation of lasonolide a analogues

Jung Min Joo
, Hyo Shin Kwak
, Jin Hyun Park
, Ho Young Song
, Eun Lee

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Homolasonolide A and 10-desmethyllasonolide A are biologically less active than lasonolide A. The ethyl ester analogue of lasonolide A exhibited higher activity than the parent compound in some biological test.

Original language	English
Pages (from-to)	1905-1908
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	14
Issue number	8
DOIs	https://doi.org/10.1016/j.bmcl.2004.01.088
Publication status	Published - 19 Apr 2004

Bibliographical note

Funding Information:
The authors thank the Ministry of Science and Technology, Republic of Korea, and KISTEP for a National Research Laboratory grant (1999). Brain Korea 21 graduate fellowship grants to H. S. Kwak and J. H. Park are gratefully acknowledged. The authors also thank Dr. ShinWu Jeong, and Mr. Ji Hyun Park of LG Life Science/R&D for the biological assay.

Keywords

10-Desmethyllasonolide A
Homolasonolide A

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10.1016/j.bmcl.2004.01.088

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@article{950f3642791d4849badfe0965156b75f,

title = "Synthesis and evaluation of lasonolide a analogues",

abstract = "Homolasonolide A and 10-desmethyllasonolide A are biologically less active than lasonolide A. The ethyl ester analogue of lasonolide A exhibited higher activity than the parent compound in some biological test.",

keywords = "10-Desmethyllasonolide A, Homolasonolide A",

author = "Joo, \{Jung Min\} and Kwak, \{Hyo Shin\} and Park, \{Jin Hyun\} and Song, \{Ho Young\} and Eun Lee",

note = "Funding Information: The authors thank the Ministry of Science and Technology, Republic of Korea, and KISTEP for a National Research Laboratory grant (1999). Brain Korea 21 graduate fellowship grants to H. S. Kwak and J. H. Park are gratefully acknowledged. The authors also thank Dr. ShinWu Jeong, and Mr. Ji Hyun Park of LG Life Science/R\&D for the biological assay.",

year = "2004",

month = apr,

day = "19",

doi = "10.1016/j.bmcl.2004.01.088",

language = "English",

volume = "14",

pages = "1905--1908",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd.",

number = "8",

}

TY - JOUR

T1 - Synthesis and evaluation of lasonolide a analogues

AU - Joo, Jung Min

AU - Kwak, Hyo Shin

AU - Park, Jin Hyun

AU - Song, Ho Young

AU - Lee, Eun

N1 - Funding Information: The authors thank the Ministry of Science and Technology, Republic of Korea, and KISTEP for a National Research Laboratory grant (1999). Brain Korea 21 graduate fellowship grants to H. S. Kwak and J. H. Park are gratefully acknowledged. The authors also thank Dr. ShinWu Jeong, and Mr. Ji Hyun Park of LG Life Science/R&D for the biological assay.

PY - 2004/4/19

Y1 - 2004/4/19

N2 - Homolasonolide A and 10-desmethyllasonolide A are biologically less active than lasonolide A. The ethyl ester analogue of lasonolide A exhibited higher activity than the parent compound in some biological test.

AB - Homolasonolide A and 10-desmethyllasonolide A are biologically less active than lasonolide A. The ethyl ester analogue of lasonolide A exhibited higher activity than the parent compound in some biological test.

KW - 10-Desmethyllasonolide A

KW - Homolasonolide A

UR - https://www.scopus.com/pages/publications/1642588149

U2 - 10.1016/j.bmcl.2004.01.088

DO - 10.1016/j.bmcl.2004.01.088

M3 - Article

C2 - 15050624

AN - SCOPUS:1642588149

SN - 0960-894X

VL - 14

SP - 1905

EP - 1908

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 8

ER -

Synthesis and evaluation of lasonolide a analogues

Abstract

Bibliographical note

Keywords

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