Abstract
Determination of gene function is particularly problematic when studying large-gene families because redundancy limits the ability to assess the contributions of individual genes experimentally. Phylogenomics is a phylogenetic approach used in comparative genomics to predict the biological functions of members of large gene-families by assessing the similarity among gene products. In this report, we describe the application of the Rice Kinase Database for elucidating functions of individual members of this gene family.
Original language | English |
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Pages (from-to) | 595-599 |
Number of pages | 5 |
Journal | Trends in Plant Science |
Volume | 15 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2010 |
Bibliographical note
Funding Information:We thank Dr. Blake Meyers and Dr. Kan Nobuta for providing MPSS signatures data, Dr. Gynheung An for providing the information about T-DNA insertional lines developed in Kyung Hee University, Korea and Dr. Harkamal Walia for useful discussions. This work was supported by a Department of Energy grant to the Joint Bioenergy Institute (Grant no. DE-AC02-05CH11231) and a National Science Foundation Plant Genome Research Program (Grant no. DBI0313887) to PCR, and a Young Scientist Program through the National Research Foundation of Korea (Grant no. 2010-0981) to KHJ.