Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study

Abdalla Z. Mohamed; Seulgi Eun; Jeungchan Lee; Kyungmo Park; Mohamed K. Metwally; Tae Song Kim; Eunyoung Lee; Seung Min Lee; Hwa Jin Lee; Sanghoon Lee; Wooseok Choi

doi:10.1109/CIBEC.2014.7020913

Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study

Abdalla Z. Mohamed, Seulgi Eun, Jeungchan Lee, Kyungmo Park, Mohamed K. Metwally, Tae Song Kim, Eunyoung Lee, Seung Min Lee, Hwa Jin Lee, Sanghoon Lee, Wooseok Choi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Bell's palsy (BP) is a common peripheral idiopathic disease affecting the facial nerve (CN VII) causing inability to move facial muscles on the affected side. We investigated BP's effects on the resting state default mode network (DMN) connectivity. Functional MRI was applied to 20 healthy volunteers and 31 BP patients at different stages with resting state. Patient's stages were defined based on disease duration and House-Brackmann Score. Dual regression approach was used for ICA based functional connectivity analysis to investigate DMN connectivity changes during different disease stages. All right sided BP patients' brain maps were flipped so that right brain hemisphere represents lesion side of the brain. It was found in this study that BP induced different brain connectivity changes within DMN varied between different stages.

Original language	English
Title of host publication	Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	51-54
Number of pages	4
ISBN (Electronic)	9781479944125
DOIs	https://doi.org/10.1109/CIBEC.2014.7020913
Publication status	Published - 23 Jan 2015
Event	7th Cairo International Biomedical Engineering Conference, CIBEC 2014 - Giza, Egypt Duration: 11 Dec 2014 → 13 Dec 2014

Publication series

Name	Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014

Conference

Conference	7th Cairo International Biomedical Engineering Conference, CIBEC 2014
Country/Territory	Egypt
City	Giza
Period	11/12/14 → 13/12/14

Bibliographical note

Publisher Copyright:
© 2014 IEEE.

Keywords

Bell's palsy
default mode network
fMRI
functional connectivity

Access to Document

10.1109/CIBEC.2014.7020913

Cite this

Mohamed, A. Z., Eun, S., Lee, J., Park, K., Metwally, M. K., Kim, T. S., Lee, E., Lee, S. M., Lee, H. J., Lee, S., & Choi, W. (2015). Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study. In Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014 (pp. 51-54). Article 7020913 (Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CIBEC.2014.7020913

Mohamed, Abdalla Z. ; Eun, Seulgi ; Lee, Jeungchan et al. / Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study. Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 51-54 (Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014).

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title = "Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study",

abstract = "Bell's palsy (BP) is a common peripheral idiopathic disease affecting the facial nerve (CN VII) causing inability to move facial muscles on the affected side. We investigated BP's effects on the resting state default mode network (DMN) connectivity. Functional MRI was applied to 20 healthy volunteers and 31 BP patients at different stages with resting state. Patient's stages were defined based on disease duration and House-Brackmann Score. Dual regression approach was used for ICA based functional connectivity analysis to investigate DMN connectivity changes during different disease stages. All right sided BP patients' brain maps were flipped so that right brain hemisphere represents lesion side of the brain. It was found in this study that BP induced different brain connectivity changes within DMN varied between different stages.",

keywords = "Bell's palsy, default mode network, fMRI, functional connectivity",

author = "Mohamed, {Abdalla Z.} and Seulgi Eun and Jeungchan Lee and Kyungmo Park and Metwally, {Mohamed K.} and Kim, {Tae Song} and Eunyoung Lee and Lee, {Seung Min} and Lee, {Hwa Jin} and Sanghoon Lee and Wooseok Choi",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 7th Cairo International Biomedical Engineering Conference, CIBEC 2014 ; Conference date: 11-12-2014 Through 13-12-2014",

year = "2015",

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doi = "10.1109/CIBEC.2014.7020913",

language = "English",

series = "Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014",

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Mohamed, AZ, Eun, S, Lee, J, Park, K, Metwally, MK, Kim, TS, Lee, E, Lee, SM, Lee, HJ, Lee, S & Choi, W 2015, Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study. in Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014., 7020913, Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014, Institute of Electrical and Electronics Engineers Inc., pp. 51-54, 7th Cairo International Biomedical Engineering Conference, CIBEC 2014, Giza, Egypt, 11/12/14. https://doi.org/10.1109/CIBEC.2014.7020913

Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study. / Mohamed, Abdalla Z.; Eun, Seulgi; Lee, Jeungchan et al.
Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014. Institute of Electrical and Electronics Engineers Inc., 2015. p. 51-54 7020913 (Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Mohamed, Abdalla Z.

AU - Eun, Seulgi

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AU - Park, Kyungmo

AU - Metwally, Mohamed K.

AU - Kim, Tae Song

AU - Lee, Eunyoung

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AU - Lee, Hwa Jin

AU - Lee, Sanghoon

AU - Choi, Wooseok

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N2 - Bell's palsy (BP) is a common peripheral idiopathic disease affecting the facial nerve (CN VII) causing inability to move facial muscles on the affected side. We investigated BP's effects on the resting state default mode network (DMN) connectivity. Functional MRI was applied to 20 healthy volunteers and 31 BP patients at different stages with resting state. Patient's stages were defined based on disease duration and House-Brackmann Score. Dual regression approach was used for ICA based functional connectivity analysis to investigate DMN connectivity changes during different disease stages. All right sided BP patients' brain maps were flipped so that right brain hemisphere represents lesion side of the brain. It was found in this study that BP induced different brain connectivity changes within DMN varied between different stages.

AB - Bell's palsy (BP) is a common peripheral idiopathic disease affecting the facial nerve (CN VII) causing inability to move facial muscles on the affected side. We investigated BP's effects on the resting state default mode network (DMN) connectivity. Functional MRI was applied to 20 healthy volunteers and 31 BP patients at different stages with resting state. Patient's stages were defined based on disease duration and House-Brackmann Score. Dual regression approach was used for ICA based functional connectivity analysis to investigate DMN connectivity changes during different disease stages. All right sided BP patients' brain maps were flipped so that right brain hemisphere represents lesion side of the brain. It was found in this study that BP induced different brain connectivity changes within DMN varied between different stages.

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Mohamed AZ, Eun S, Lee J, Park K, Metwally MK, Kim TS et al. Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study. In Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014. Institute of Electrical and Electronics Engineers Inc. 2015. p. 51-54. 7020913. (Proceedings of the 7th Cairo International Biomedical Engineering Conference, CIBEC 2014). doi: 10.1109/CIBEC.2014.7020913

Unilateral facial nerve paralysis induced changes in DMN functional connectivity; A fMRI study

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Keywords

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