Visible-Light-Mediated Cross-Couplings and C−H Activation via Dual Photoredox/Transition-Metal Catalysis in Continuous-Flow Processes

Soo Dong Kim; Jonghyun Lee; Nam Jung Kim; Boyoung Y. Park

doi:10.1002/ajoc.201900354

Visible-Light-Mediated Cross-Couplings and C−H Activation via Dual Photoredox/Transition-Metal Catalysis in Continuous-Flow Processes

Soo Dong Kim, Jonghyun Lee, Nam Jung Kim, Boyoung Y. Park

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Herein, we review dual photoredox/transition-metal catalysis for C−C/C−N cross-couplings and C−H activation in continuous-flow processes. Compared to conventional transition-metal catalysis for these reactions, visible-light-mediated synergistic catalysis enables the use of relatively mild and environmentally friendly reaction conditions by decreasing the activation energy and using a renewable energy source. However, photochemical transformations in batch processing have limitations such as reactivity, reaction time, substrate scope, and scalability due to light attenuation as represented by the Beer-Lambert law. In this review article, we therefore summarize and discuss several examples of cross-couplings and C−H activation in continuous-flow processes that overcome these problems in batch processing.

Original language	English
Pages (from-to)	1578-1587
Number of pages	10
Journal	Asian Journal of Organic Chemistry
Volume	8
Issue number	9
DOIs	https://doi.org/10.1002/ajoc.201900354
Publication status	Published - 1 Sept 2019

Bibliographical note

Publisher Copyright:
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Keywords

C−H activation
continuous-flow processes
cross-coupling
photochemical transformations

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/ajoc.201900354

Cite this

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title = "Visible-Light-Mediated Cross-Couplings and C−H Activation via Dual Photoredox/Transition-Metal Catalysis in Continuous-Flow Processes",

abstract = "Herein, we review dual photoredox/transition-metal catalysis for C−C/C−N cross-couplings and C−H activation in continuous-flow processes. Compared to conventional transition-metal catalysis for these reactions, visible-light-mediated synergistic catalysis enables the use of relatively mild and environmentally friendly reaction conditions by decreasing the activation energy and using a renewable energy source. However, photochemical transformations in batch processing have limitations such as reactivity, reaction time, substrate scope, and scalability due to light attenuation as represented by the Beer-Lambert law. In this review article, we therefore summarize and discuss several examples of cross-couplings and C−H activation in continuous-flow processes that overcome these problems in batch processing.",

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AU - Park, Boyoung Y.

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Visible-Light-Mediated Cross-Couplings and C−H Activation via Dual Photoredox/Transition-Metal Catalysis in Continuous-Flow Processes

Abstract

Bibliographical note

Keywords

UN SDGs

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